Detailed immune monitoring of a pregnant woman with critical Covid-19.
J Reprod Immunol
; 143: 103243, 2021 02.
Article
in English
| MEDLINE | ID: covidwho-894079
ABSTRACT
A primigravid woman with Covid-19 related respiratory insufficiency was admitted into a tertiary Intensive Care Unit at 23 3/7 weeks' gestation. Highly sensitive flow cytometry of peripheral leukocytes indicated significantly suppressed naïve T- and B-cell compartments. The suppressed immune cell responses led us keep the initially started administration of corticosteroids for fetal and maternal indication at a low dose. After three weeks her B-cell response peaked, SARS-CoV-2 was cleared and clinical improvement ensued a week later. At 28 weeks' gestation, a son of 1570 g was born by cesarean section. She was extubated two days postpartum and discharged from hospital 5.5 weeks postpartum.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pregnancy Complications, Infectious
/
Respiratory Insufficiency
/
Pregnancy
/
B-Lymphocytes
/
T-Lymphocytes
/
SARS-CoV-2
/
COVID-19
Type of study:
Case report
/
Diagnostic study
/
Prognostic study
Limits:
Adult
/
Female
/
Humans
Language:
English
Journal:
J Reprod Immunol
Year:
2021
Document Type:
Article
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