Your browser doesn't support javascript.
COVID-19 myocarditis and prospective heart failure burden.
Shchendrygina, Anastasia; Nagel, Eike; Puntmann, Valentina O; Valbuena-Lopez, Silvia.
  • Shchendrygina A; Department of Hospital Therapy №1, I.M. Sechenov First Moscow State Medical University (Sechenov University) , Moscow, Russian Federation.
  • Nagel E; Institute for Experimental and Translational Cardiovascular Imaging, Goethe University Hospital Frankfurt , Frankfurt, Germany.
  • Puntmann VO; Department of Cardiology, Division of Internal Medicine III, Goethe University Hospital Frankfurt , Frankfurt, Germany.
  • Valbuena-Lopez S; Department of Cardiology, University Hospital La Paz , Madrid, Spain.
Expert Rev Cardiovasc Ther ; 19(1): 5-14, 2021 Jan.
Article in English | MEDLINE | ID: covidwho-894500
ABSTRACT

Introduction:

COVID-19 is causing considerable morbidity and mortality worldwide. Serious respiratory complications aside, the heart is also frequently involved. The mechanisms and the extent of the myocardial injury, along with the short and long-term cardiovascular (CV) outcomes in COVID-19 survivors remain unclear. Areas covered myocardial injury has been found in a considerable proportion of hospitalized COVID-19 patients and is associated with a worse prognosis. The late onset of CV complications with myocarditis-like changes revealed by CMR has been reported in COVID-19 survivors. Previous observational studies on viral myocarditis provide evidence of a significant incomplete recovery with residual dysfunction and remodeling of left ventricle. Incomplete recovery is thought to be the result of persistent myocardial inflammation due to a post-viral autoimmune response. Considering the significant inflammatory nature of COVID-19, COVID-19 survivors may be at risk of developing persistent residual myocardial injury, the sequelae of which are unclear. Expert commentary COVID-19 is an emerging threat for the heart. The extent of CV injury, along with the short and long-term sequelae, requires further investigation. The early detection of residual myocardial changes in COVID-19 survivors is of utmost importance in order to identify those patients at risk of CV complication development.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Heart Failure / Cardiomyopathies / Myocarditis Type of study: Cohort study / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Expert Rev Cardiovasc Ther Journal subject: Vascular Diseases / Cardiology / Therapeutics Year: 2021 Document Type: Article

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 / Heart Failure / Cardiomyopathies / Myocarditis Type of study: Cohort study / Observational study / Prognostic study Topics: Long Covid Limits: Humans Language: English Journal: Expert Rev Cardiovasc Ther Journal subject: Vascular Diseases / Cardiology / Therapeutics Year: 2021 Document Type: Article