SARS-CoV-2 infection in a patient with propionic acidemia.
Orphanet J Rare Dis
; 15(1): 306, 2020 10 28.
Article
in English
| MEDLINE | ID: covidwho-895014
ABSTRACT
We describe a 14-month-old boy, with a previous diagnosis of propionic acidemia (PA) by expanded newborn screening, who, admitted for a suspected metabolic crisis, tested positive for SARS-CoV-2. Since propionic acidemia was diagnosed, the patient has followed the recommended diet for this inborn error of metabolism. Although propionic acidemia patients are at a high risk of suffering metabolic crises, frequently associated with permanent clinical complications, psychomotor development of this patient was normal. The SARS-CoV-2 infection (at about 1 year of age) caused the patient's first metabolic crisis. However, his clinical course was in keeping with a mild clinical form of COVID-19, and he recovered without experiencing severe clinical consequences. We describe this patient in order to improve the knowledge about follow up of PA patients identified by newborn screening and to increase the limited number of reports of SARS-CoV-2 infection in children with comorbidities, especially inborn errors of metabolism.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Neonatal Screening
/
Coronavirus Infections
/
Propionic Acidemia
Type of study:
Case report
/
Cohort study
/
Diagnostic study
/
Prognostic study
Topics:
Long Covid
Limits:
Humans
/
Infant
/
Male
/
Infant, Newborn
Language:
English
Journal:
Orphanet J Rare Dis
Journal subject:
Medicine
Year:
2020
Document Type:
Article
Affiliation country:
S13023-020-01563-w
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