Influenza and pneumonia-attributed deaths among cancer patients in the United States; a population-based study.
Expert Rev Respir Med
; 15(3): 393-401, 2021 03.
Article
in English
| MEDLINE | ID: covidwho-897071
ABSTRACT
Objective:
To assess the patterns and trends of influenza and pneumonia-attributed deaths among cancer patients in the United States.Methods:
Surveillance, Epidemiology and End Results (SEER) database was accessed and cancer patients diagnosed 1975-2016 who have been included in the SEER-9 registries were included. The primary endpoint of the study is standardized mortality rate (SMR; calculated as observed/ Expected (O/E) ratio for death from influenza and pneumonia among cancer patients).Results:
The current study evaluates a total of 3,579,199 cancer patients (diagnosed 1975-2016) within the SEER-9 registries; and influenza and pneumonia-attributed deaths represent 1.5% of the recorded deaths for this cohort. SMR for influenza/ pneumonia-attributed death within the first year following cancer diagnosis was 1.88 (1.83-1.94);while SMR for influenza/pneumonia-attributed death following the first year was 1.11 (1.10-1.12). Within the first year following cancer diagnosis, SMR from influenza/pneumonia was higher among individuals with black race (SMR for white race 1.75 (95% CI 1.69-1.81) while SMR for black race 2.90 (95% CI 2.65-3.16), lung cancer (SMR for lung cancer 4.39 (95% CI 4.11-4.69)), head and neck cancer (SMR for oral cavity/ pharynx cancer 4.02 (95% CI 3.50-4.59)), lymphomas (SMR for lymphoma 3.28 (95% CI 2.92-3.68)), leukemias (SMR for leukemia 3.32 (95% CI 2.89-3.80)) and myeloma (SMR for myeloma 3.91 (95% CI 3.28-4.63)).Conclusions:
Cancer patients are more likely to have influenza/ pneumonia-attributed death compared to the general US population. This risk is higher among patients with lung cancer, head and neck cancer, and hematological malignancies.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia
/
Influenza, Human
/
Lung Neoplasms
/
Occupational Diseases
Type of study:
Cohort study
/
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
Limits:
Humans
Country/Region as subject:
North America
Language:
English
Journal:
Expert Rev Respir Med
Year:
2021
Document Type:
Article
Affiliation country:
17476348.2021.1842203
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