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SARS-CoV-2 Viral Load on Admission Is Associated With 30-Day Mortality.
Bryan, Andrew; Fink, Susan L; Gattuso, Meghan A; Pepper, Gregory; Chaudhary, Anu; Wener, Mark H; Morishima, Chihiro; Jerome, Keith R; Mathias, Patrick C; Greninger, Alexander L.
  • Bryan A; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA.
  • Fink SL; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA.
  • Gattuso MA; Aquaelis, LLC, Seattle, Washington, USA.
  • Pepper G; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA.
  • Chaudhary A; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA.
  • Wener MH; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA.
  • Morishima C; Department of Medicine, University of Washington School of Medicine, Seattle, Washington, USA.
  • Jerome KR; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA.
  • Mathias PC; Department of Laboratory Medicine and Pathology, University of Washington School of Medicine, Seattle, Washington, USA.
  • Greninger AL; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA.
Open Forum Infect Dis ; 7(12): ofaa535, 2020 Dec.
Article in English | MEDLINE | ID: covidwho-900465
ABSTRACT
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) viral load on admission was associated with a significantly increased 30-day mortality (odds ratio [OR], 4.20; 95% CI, 1.62-10.86), and anti-SARS-CoV-2 nucleocapisid IgG seropositivity on admission trended toward a reduced 30-day mortality (OR, 0.43; 95% CI, 0.15-1.26). Reporting of quantitative SARS-CoV-2 viral load and serologic assays may offer prognostic clinical information.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: Open Forum Infect Dis Year: 2020 Document Type: Article Affiliation country: Ofid

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Prognostic study Language: English Journal: Open Forum Infect Dis Year: 2020 Document Type: Article Affiliation country: Ofid