Clinical course of COVID-19 among immunocompromised children: a clinical case series.
BMJ Case Rep
; 13(10)2020 Oct 31.
Article
in English
| MEDLINE | ID: covidwho-901288
ABSTRACT
Infection with SARS-CoV-2 represents a great source of concern and a new threat for immunocompromised patients. Limited studies are available on COVID-19 in immunocompromised children. This case series aimed to evaluate the clinical and laboratory characteristics, management and outcomes of COVID-19 in five children immunocompromised due to different underlying conditions. All had mild symptoms or were asymptomatic at presentation. All had a benign course of illness. No changes or delays in their treatment regimens occurred, and none experienced a relapse of the original disease, developed severe COVID-19 or died. However, these cases showed a prolonged duration of virus shedding. This report suggests that immunocompromised paediatric patients may not be at a higher risk of developing severe COVID-19. However, further studies are required to elaborate on the pathogenesis of COVID-19 in this vulnerable group.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Immunocompromised Host
/
Coronavirus Infections
/
Severe Acute Respiratory Syndrome
/
Pandemics
Type of study:
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
Limits:
Child
/
Child, preschool
/
Female
/
Humans
/
Male
Language:
English
Year:
2020
Document Type:
Article
Affiliation country:
Bcr-2020-237804
Similar
MEDLINE
...
LILACS
LIS