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An Overview on SARS-CoV-2 (COVID-19) and Other Human Coronaviruses and Their Detection Capability via Amplification Assay, Chemical Sensing, Biosensing, Immunosensing, and Clinical Assays.
Orooji, Yasin; Sohrabi, Hessamaddin; Hemmat, Nima; Oroojalian, Fatemeh; Baradaran, Behzad; Mokhtarzadeh, Ahad; Mohaghegh, Mohamad; Karimi-Maleh, Hassan.
  • Orooji Y; College of Materials Science and Engineering, Nanjing Forestry University, Nanjing, 210037 People's Republic of China.
  • Sohrabi H; Jiangsu Co-Innovation Center for Efficient Processing and Utilization of Forest Resources, Nanjing Forestry University, Nanjing, 210037 People's Republic of China.
  • Hemmat N; Department of Analytical Chemistry, Faculty of Chemistry, University of Tabriz, Tabriz, 51666-16471 Iran.
  • Oroojalian F; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Baradaran B; Department of Advanced Sciences and Technologies in Medicine, School of Medicine, North Khorasan University of Medical Sciences, Bojnurd, Iran.
  • Mokhtarzadeh A; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Mohaghegh M; Immunology Research Center, Tabriz University of Medical Sciences, Tabriz, Iran.
  • Karimi-Maleh H; Department of Nanobiotechnology, School of Biological Sciences, Tarbiat Modares University, Tehran, Iran.
Nanomicro Lett ; 13(1): 18, 2021.
Article in English | MEDLINE | ID: covidwho-911984
Semantic information from SemMedBD (by NLM)
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Coronavirus Infections
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Patients
3. SARS coronavirus PROCESS_OF Chiroptera
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SARS coronavirus
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Chiroptera
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7. Screening procedure DIAGNOSES Virus
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8. Polymerase Chain Reaction DIAGNOSES Virus
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DIAGNOSES
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PROCESS_OF
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Assay
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DIAGNOSES
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ABSTRACT
A novel coronavirus of zoonotic origin (SARS-CoV-2) has recently been recognized in patients with acute respiratory disease. COVID-19 causative agent is structurally and genetically similar to SARS and bat SARS-like coronaviruses. The drastic increase in the number of coronavirus and its genome sequence have given us an unprecedented opportunity to perform bioinformatics and genomics analysis on this class of viruses. Clinical tests like PCR and ELISA for rapid detection of this virus are urgently needed for early identification of infected patients. However, these techniques are expensive and not readily available for point-of-care (POC) applications. Currently, lack of any rapid, available, and reliable POC detection method gives rise to the progression of COVID-19 as a horrible global problem. To solve the negative features of clinical investigation, we provide a brief introduction of the general features of coronaviruses and describe various amplification assays, sensing, biosensing, immunosensing, and aptasensing for the determination of various groups of coronaviruses applied as a template for the detection of SARS-CoV-2. All sensing and biosensing techniques developed for the determination of various classes of coronaviruses are useful to recognize the newly immerged coronavirus, i.e., SARS-CoV-2. Also, the introduction of sensing and biosensing methods sheds light on the way of designing a proper screening system to detect the virus at the early stage of infection to tranquilize the speed and vastity of spreading. Among other approaches investigated among molecular approaches and PCR or recognition of viral diseases, LAMP-based methods and LFAs are of great importance for their numerous benefits, which can be helpful to design a universal platform for detection of future emerging pathogenic viruses.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study / Experimental Studies / Prognostic study / Randomized controlled trials Language: English Journal: Nanomicro Lett Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study / Experimental Studies / Prognostic study / Randomized controlled trials Language: English Journal: Nanomicro Lett Year: 2021 Document Type: Article