COVID-19 and COPD: a narrative review of the basic science and clinical outcomes.
Eur Respir Rev
; 29(158)2020 Dec 31.
Article
in English
| MEDLINE | ID: covidwho-914011
ABSTRACT
The 2019 coronavirus disease (COVID-19) pandemic is caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2). Clinical outcomes, including mortality, are worse in males, older individuals and patients with comorbidities. COPD patients are included in shielding strategies due to their susceptibility to virus-induced exacerbations, compromised pulmonary function and high prevalence of associated comorbidities. Using evidence from basic science and cohort studies, this review addresses key questions concerning COVID-19 and COPD. First, are there mechanisms by which COPD patients are more susceptible to SARS-CoV-2 infection? Secondly, do inhaled corticosteroids offer protection against COVID-19? And, thirdly, what is the evidence regarding clinical outcomes from COVID-19 in COPD patients? This up-to-date review tackles some of the key issues which have significant impact on the long-term outlook for COPD patients in the context of COVID-19.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Coronavirus Infections
/
Disease Progression
/
Pulmonary Disease, Chronic Obstructive
/
Disease Susceptibility
Type of study:
Cohort study
/
Diagnostic study
/
Observational study
/
Prognostic study
/
Reviews
Topics:
Long Covid
Limits:
Adult
/
Aged
/
Humans
/
Middle aged
Language:
English
Year:
2020
Document Type:
Article
Affiliation country:
16000617.0199-2020
Similar
MEDLINE
...
LILACS
LIS