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Controlled Heat and Humidity-Based Treatment for the Reuse of Personal Protective Equipment: A Pragmatic Proof-of-Concept to Address the Mass Shortage of Surgical Masks and N95/FFP2 Respirators and to Prevent the SARS-CoV2 Transmission.
Bernard, Louis; Desoubeaux, Guillaume; Bodier-Montagutelli, Elsa; Pardessus, Jeoffrey; Brea, Déborah; Allimonnier, Laurine; Eymieux, Sébastien; Raynal, Pierre-Ivan; Vasseur, Virginie; Vecellio, Laurent; Mathé, Ludovic; Guillon, Antoine; Lanotte, Philippe; Pourchez, Jérémie; Verhoeven, Paul O; Esnouf, Stéphane; Ferry, Muriel; Eterradossi, Nicolas; Blanchard, Yannick; Brown, Paul; Roingeard, Philippe; Alcaraz, Jean-Pierre; Cinquin, Philippe; Si-Tahar, Mustapha; Heuzé-Vourc'h, Nathalie.
  • Bernard L; Médecine interne et maladies infectieuses, CHU de Tours, Tours, France.
  • Desoubeaux G; Université de Tours, Tours, France.
  • Bodier-Montagutelli E; Université de Tours, Tours, France.
  • Pardessus J; Parasitologie-mycologie-médecine tropicale, CHU de Tours, Tours, France.
  • Brea D; Inserm U1100, Centre d'étude des pathologies respiratoires (CEPR), Tours, France.
  • Allimonnier L; Université de Tours, Tours, France.
  • Eymieux S; Inserm U1100, Centre d'étude des pathologies respiratoires (CEPR), Tours, France.
  • Raynal PI; Pharmacie à usage intérieure, CHU de Tours, Tours, France.
  • Vasseur V; Université de Tours, Tours, France.
  • Vecellio L; Inserm U1100, Centre d'étude des pathologies respiratoires (CEPR), Tours, France.
  • Mathé L; Université de Tours, Tours, France.
  • Guillon A; Inserm U1100, Centre d'étude des pathologies respiratoires (CEPR), Tours, France.
  • Lanotte P; Université de Tours, Tours, France.
  • Pourchez J; Inserm U1100, Centre d'étude des pathologies respiratoires (CEPR), Tours, France.
  • Verhoeven PO; Université de Tours, Tours, France.
  • Esnouf S; Biologie cellulaire-Microscopie électronique, CHU de Tours, Tours, France.
  • Ferry M; UMR Inserm U1259-Morphogénèse et antigénicité du VIH et des virus des hépatites, Tours, France.
  • Eterradossi N; Université de Tours, Tours, France.
  • Blanchard Y; Biologie cellulaire-Microscopie électronique, CHU de Tours, Tours, France.
  • Brown P; Université de Tours, Tours, France.
  • Roingeard P; Inserm U1100, Centre d'étude des pathologies respiratoires (CEPR), Tours, France.
  • Alcaraz JP; Université de Tours, Tours, France.
  • Cinquin P; Inserm U1100, Centre d'étude des pathologies respiratoires (CEPR), Tours, France.
  • Si-Tahar M; Blanchisserie centrale GCS NOT, CHU de Tours, Tours, France.
  • Heuzé-Vourc'h N; Université de Tours, Tours, France.
Front Med (Lausanne) ; 7: 584036, 2020.
Article in English | MEDLINE | ID: covidwho-914431
ABSTRACT

Background:

The coronavirus infectious disease-2019 (COVID-19) pandemic has led to an unprecedented shortage of healthcare resources, primarily personal protective equipment like surgical masks, and N95/filtering face piece type 2 (FFP2) respirators.

Objective:

Reuse of surgical masks and N95/FFP2 respirators may circumvent the supply chain constraints and thus overcome mass shortage. Methods, design, setting, and measurement Herein, we tested the effects of dry- and moist-air controlled heating treatment on structure and chemical integrity, decontamination yield, and filtration performance of surgical masks and FFP2 respirators.

Results:

We found that treatment in a climate chamber at 70°C during 1 h with 75% humidity rate was adequate for enabling substantial decontamination of both respiratory viruses, oropharyngeal bacteria, and model animal coronaviuses, while maintaining a satisfying filtering capacity.

Limitations:

Further studies are now required to confirm the feasibility of the whole process during routine practice.

Conclusion:

Our findings provide compelling evidence for the recycling of pre-used surgical masks and N95/FFP2 respirators in case of imminent mass shortfall.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies Language: English Journal: Front Med (Lausanne) Year: 2020 Document Type: Article Affiliation country: Fmed.2020.584036

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Experimental Studies Language: English Journal: Front Med (Lausanne) Year: 2020 Document Type: Article Affiliation country: Fmed.2020.584036