Case Report: Disseminated Strongyloidiasis in a Patient with COVID-19.

Lier, Audun J; Tuan, Jessica J; Davis, Matthew W; Paulson, Nathan; McManus, Dayna; Campbell, Sheldon; Peaper, David R; Topal, Jeffrey E

Lier, Audun J; Tuan, Jessica J; Davis, Matthew W; Paulson, Nathan; McManus, Dayna; Campbell, Sheldon; Peaper, David R; Topal, Jeffrey E.

Lier AJ; 1Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Tuan JJ; 1Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.
Davis MW; 2Department of Pharmacy Services, Yale New Haven Hospital, New Haven, Connecticut.
Paulson N; 3Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut.
McManus D; 2Department of Pharmacy Services, Yale New Haven Hospital, New Haven, Connecticut.
Campbell S; 3Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut.
Peaper DR; 3Department of Laboratory Medicine, Yale University School of Medicine, New Haven, Connecticut.
Topal JE; 1Section of Infectious Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, Connecticut.

Am J Trop Med Hyg ; 103(4): 1590-1592, 2020 10.

Article in English | MEDLINE | ID: covidwho-914663

ABSTRACT

ABSTRACT

The SARS-CoV-2 virus has emerged and rapidly evolved into a current global pandemic. Although bacterial and fungal coinfections have been associated with COVID-19, little is known about parasitic infection. We report a case of a COVID-19 patient who developed disseminated strongyloidiasis following treatment with high-dose corticosteroids and tocilizumab. Screening for Strongyloides infection should be pursued in individuals with COVID-19 who originate from endemic regions before initiating immunosuppressive therapy.

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Coronavirus Infections/parasitology; Diabetes Mellitus/parasitology; Hypertension/parasitology; Peripheral Nervous System Diseases/parasitology; Pneumonia, Viral/parasitology; Strongyloides stercoralis/pathogenicity; Strongyloidiasis/parasitology; Adrenal Cortex Hormones/administration & dosage; Aged; Animals; Anthelmintics/therapeutic use; Antibodies, Monoclonal, Humanized/administration & dosage; Betacoronavirus/pathogenicity; COVID-19; Coinfection; Connecticut; Coronavirus Infections/drug therapy; Coronavirus Infections/immunology; Coronavirus Infections/virology; Diabetes Mellitus/drug therapy; Diabetes Mellitus/immunology; Diabetes Mellitus/virology; Ecuador; Humans; Hypertension/drug therapy; Hypertension/immunology; Hypertension/virology; Immunologic Factors/administration & dosage; Male; Pandemics; Peripheral Nervous System Diseases/drug therapy; Peripheral Nervous System Diseases/immunology; Peripheral Nervous System Diseases/virology; Pneumonia, Viral/drug therapy; Pneumonia, Viral/immunology; Pneumonia, Viral/virology; SARS-CoV-2; Strongyloidiasis/drug therapy; Strongyloidiasis/immunology; Strongyloidiasis/virology

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Strongyloidiasis / Strongyloides stercoralis / Coronavirus Infections / Peripheral Nervous System Diseases / Diabetes Mellitus / Hypertension Type of study: Case report Country/Region as subject: North America / South America / Ecuador Language: English Journal: Am J Trop Med Hyg Year: 2020 Document Type: Article

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