Isolated immune thrombocytopenic purpura in a young adult Covid-19 patient.
Eur Rev Med Pharmacol Sci
; 24(20): 10850-10852, 2020 10.
Article
in English
| MEDLINE | ID: covidwho-914959
ABSTRACT
OBJECTIVE:
Patients with Covid-19 can have different symptoms, ranging from asymptomatic patients to various grades of respiratory failure, caused by typical interstitial pneumonia, cardiac involvement or neurological symptoms. PATIENTS ANDMETHODS:
In April 2020, we focused our attention on a young woman with diffused purpura on her lower extremities, with no respiratory, cardiac or neurological symptoms. A complete blood analysis showed us a severe thrombocytopenia. We excluded other possible causes of thrombocytopenic purpura such as hematological (lymphocyte subsets), hepatological disease or splenomegaly. On autoimmune screening, we found Isolated immune thrombocytopenic purpura in a young adult Covid-19 patient positivity of anti-nuclear antibody (ANA) with a centrosome pattern and extractable nuclear antigens (ENA) and connective tissue disease screen resulted positive but none of the included specific antigens results positive, probably due to an aspecific antibody reaction. The wide variability of COVID disease presentation may be due to a personal different immune response to the virus.CONCLUSIONS:
The immune response against the virus is crucial in the evolution and understanding of COVID-19 disease but it has still to be fully understood.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Purpura, Thrombocytopenic, Idiopathic
/
Coronavirus Infections
Type of study:
Case report
/
Diagnostic study
Topics:
Long Covid
Limits:
Adult
/
Female
/
Humans
/
Young adult
Language:
English
Journal:
Eur Rev Med Pharmacol Sci
Journal subject:
Pharmacology
/
Toxicology
Year:
2020
Document Type:
Article
Affiliation country:
Eurrev_202010_23447
Similar
MEDLINE
...
LILACS
LIS