Charlson comorbidity index and a composite of poor outcomes in COVID-19 patients: A systematic review and meta-analysis.
Diabetes Metab Syndr
; 14(6): 2103-2109, 2020.
Article
in English
| MEDLINE | ID: covidwho-915414
ABSTRACT
BACKGROUND AND AIMS:
The ongoing COVID-19 pandemic is disproportionately affecting patients with comorbidities. Therefore, thorough comorbidities assessment can help establish risk stratification of patients with COVID-19, upon hospital admission. Charlson Comorbidity Index (CCI) is a validated, simple, and readily applicable method of estimating the risk of death from comorbid disease and has been widely used as a predictor of long-term prognosis and survival.METHODS:
We performed a systematic review and meta-analysis of CCI score and a composite of poor outcomes through several databases.RESULTS:
Compared to a CCI score of 0, a CCI score of 1-2 and CCI score of ≥3 was prognostically associated with mortality and associated with a composite of poor outcomes. Per point increase of CCI score also increased mortality risk by 16%. Moreover, a higher mean CCI score also significantly associated with mortality and disease severity.CONCLUSION:
CCI score should be utilized for risk stratifications of hospitalized COVID-19 patients.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
COVID-19
/
Hospitalization
Type of study:
Cohort study
/
Diagnostic study
/
Observational study
/
Prognostic study
/
Reviews
/
Systematic review/Meta Analysis
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
Diabetes Metab Syndr
Year:
2020
Document Type:
Article
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