Experience of SARS-CoV-2 infection in two kidney transplant recipients living with HIV-1 infection.

Chowdary, Prashanth; Shetty, Shraddha; Booth, John; Khurram, Muhammad Arslan; Yaqoob, Magdi; Mohamed, Ismail Heyder

Chowdary, Prashanth; Shetty, Shraddha; Booth, John; Khurram, Muhammad Arslan; Yaqoob, Magdi; Mohamed, Ismail Heyder.

Chowdary P; Department of Renal Medicine and Transplantation, The Royal London Hospital, London, UK.
Shetty S; Department of Renal Medicine and Transplantation, The Royal London Hospital, London, UK.
Booth J; Department of Renal Medicine and Transplantation, The Royal London Hospital, London, UK.
Khurram MA; Department of Renal Medicine and Transplantation, The Royal London Hospital, London, UK.
Yaqoob M; Department of Renal Medicine and Transplantation, The Royal London Hospital, London, UK.
Mohamed IH; Department of Renal Medicine and Transplantation, The Royal London Hospital, London, UK.

Transpl Infect Dis ; 23(2): e13500, 2021 Apr.

Article in English | MEDLINE | ID: covidwho-916948

ABSTRACT

ABSTRACT

There is still no consensus on the optimal management of COVID-19 within the general population due to the emerging evidence base. High-risk groups, including kidney transplant recipients living with HIV present unique additional challenges. Here we discuss two kidney transplant recipients living with HIV with SARS-CoV-2 infection and their clinical course, and review the existing literature for this subset of challenging patients.

Subject(s)

Anti-HIV Agents/therapeutic use; COVID-19/therapy; Glucocorticoids/therapeutic use; Graft Rejection/prevention & control; HIV Infections/drug therapy; Immunosuppressive Agents/therapeutic use; Kidney Transplantation; Adult; Anti-Bacterial Agents/therapeutic use; Atovaquone/therapeutic use; CD4 Lymphocyte Count; CD4-CD8 Ratio; COVID-19/complications; COVID-19/immunology; Dideoxynucleosides/therapeutic use; Female; HIV Infections/complications; HIV Infections/immunology; HIV-1/genetics; Humans; Immunocompromised Host/immunology; Lamivudine/therapeutic use; Male; Middle Aged; Mycophenolic Acid/therapeutic use; Pneumonia, Pneumocystis/prevention & control; Prednisolone/therapeutic use; RNA, Viral; Raltegravir Potassium/therapeutic use; SARS-CoV-2; Tacrolimus/therapeutic use; Trimethoprim, Sulfamethoxazole Drug Combination/therapeutic use

Keywords

COVID-19; HIV; SARS-CoV-2; calcineurin inhibitor; renal transplant; transplantation

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Full text: Available Collection: International databases Database: MEDLINE Main subject: HIV Infections / Kidney Transplantation / Anti-HIV Agents / COVID-19 / Glucocorticoids / Graft Rejection / Immunosuppressive Agents Type of study: Case report / Experimental Studies / Prognostic study / Randomized controlled trials Topics: Long Covid Limits: Adult / Female / Humans / Male / Middle aged Language: English Journal: Transpl Infect Dis Journal subject: Transplantation Year: 2021 Document Type: Article Affiliation country: Tid.13500

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