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AI-assisted CT imaging analysis for COVID-19 screening: Building and deploying a medical AI system.
Wang, Bo; Jin, Shuo; Yan, Qingsen; Xu, Haibo; Luo, Chuan; Wei, Lai; Zhao, Wei; Hou, Xuexue; Ma, Wenshuo; Xu, Zhengqing; Zheng, Zhuozhao; Sun, Wenbo; Lan, Lan; Zhang, Wei; Mu, Xiangdong; Shi, Chenxi; Wang, Zhongxiao; Lee, Jihae; Jin, Zijian; Lin, Minggui; Jin, Hongbo; Zhang, Liang; Guo, Jun; Zhao, Benqi; Ren, Zhizhong; Wang, Shuhao; Xu, Wei; Wang, Xinghuan; Wang, Jianming; You, Zheng; Dong, Jiahong.
  • Wang B; State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing, China.
  • Jin S; Beijing Innovation Center for Future Chips, Tsinghua University, Beijing, China.
  • Yan Q; Beijing Jingzhen Medical Technology Ltd., Beijing, China.
  • Xu H; Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
  • Luo C; Institute for Precision Medicine, Tsinghua University, Beijing, China.
  • Wei L; University of Adelaide, SA, Australia.
  • Zhao W; Beijing Jingzhen Medical Technology Ltd., Beijing, China.
  • Hou X; Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Ma W; State Key Laboratory of Precision Measurement Technology and Instruments, Department of Precision Instrument, Tsinghua University, Beijing, China.
  • Xu Z; Beijing Laboratory for Biomedical Detection Technology and Instrument, Tsinghua University, Beijing, China.
  • Zheng Z; Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
  • Sun W; Institute for Precision Medicine, Tsinghua University, Beijing, China.
  • Lan L; Beijing Jingzhen Medical Technology Ltd., Beijing, China.
  • Zhang W; Beijing Jingzhen Medical Technology Ltd., Beijing, China.
  • Mu X; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.
  • Shi C; Beijing Jingzhen Medical Technology Ltd., Beijing, China.
  • Wang Z; Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
  • Lee J; Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Jin Z; Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China.
  • Lin M; Beijing Jingzhen Medical Technology Ltd., Beijing, China.
  • Jin H; School of Telecommunication Engineering, Xidian University, Xi'an, China.
  • Zhang L; Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
  • Guo J; Institute for Precision Medicine, Tsinghua University, Beijing, China.
  • Zhao B; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.
  • Ren Z; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.
  • Wang S; Institute for Interdisciplinary Information Sciences, Tsinghua University, Beijing, China.
  • Xu W; Beijing Jingzhen Medical Technology Ltd., Beijing, China.
  • Wang X; Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
  • Wang J; Beijing Jingzhen Medical Technology Ltd., Beijing, China.
  • You Z; School of Computer Science and Technology, Xidian University, Xi'an, China.
  • Dong J; Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing, China.
Appl Soft Comput ; 98: 106897, 2021 Jan.
Article in English | MEDLINE | ID: covidwho-917218
ABSTRACT
The sudden outbreak of novel coronavirus 2019 (COVID-19) increased the diagnostic burden of radiologists. In the time of an epidemic crisis, we hope artificial intelligence (AI) to reduce physician workload in regions with the outbreak, and improve the diagnosis accuracy for physicians before they could acquire enough experience with the new disease. In this paper, we present our experience in building and deploying an AI system that automatically analyzes CT images and provides the probability of infection to rapidly detect COVID-19 pneumonia. The proposed system which consists of classification and segmentation will save about 30%-40% of the detection time for physicians and promote the performance of COVID-19 detection. Specifically, working in an interdisciplinary team of over 30 people with medical and/or AI background, geographically distributed in Beijing and Wuhan, we are able to overcome a series of challenges (e.g. data discrepancy, testing time-effectiveness of model, data security, etc.) in this particular situation and deploy the system in four weeks. In addition, since the proposed AI system provides the priority of each CT image with probability of infection, the physicians can confirm and segregate the infected patients in time. Using 1,136 training cases (723 positives for COVID-19) from five hospitals, we are able to achieve a sensitivity of 0.974 and specificity of 0.922 on the test dataset, which included a variety of pulmonary diseases.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study Language: English Journal: Appl Soft Comput Year: 2021 Document Type: Article Affiliation country: J.asoc.2020.106897

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study Language: English Journal: Appl Soft Comput Year: 2021 Document Type: Article Affiliation country: J.asoc.2020.106897