Colombian consensus for the prevention, diagnosis and treatment of thrombotic conditions in adults with COVID-19: applying GRADE Evidence to Decision (EtD) Frameworks

Acevedo-Peña, J., Yomayusa-González, N., Cantor-Cruz, F., Pinzón-Flórez, C., Barrero-Garzón, L., De-La-Hoz-Siegler, I., Low-Padilla, E., Ramírez-Cerón, C., Combariza-Vallejo, F., Arias-Barrera, C., Moreno-Cortés, J., Rozo-Vanstrahlen, J., Correa-Pérez, L., Rojas-Gambasica, J., González-González, C., La-Rotta-Caballero, E., Ruíz-Talero, P., Contreras-Páez, R., Lineros-Montañez, A., Ordoñez-Cardales, J., Escobar-Olaya, M., Izaguirre-Ávila, R., Campos-Guerra, J., Accini-Mendoza, J., Pizarro-Gómez, C., Patiño-Pérez, A., Flores-Rodríguez, J., Valencia-Moreno, A., Londoño-Villegas, A., Saavedra-Rodríguez, A., Madera-Rojas, A., Caballero-Arteagam, A., Díaz-Campos, A., Correa-Rivera, F., Mantilla-Reinaud, A., Becerra-Torres, Á, Peña-Castellanos, Á, Reina-Soler, A., Escobar-Suarez, B., Patiño-Escobar, B., Rodríguez-Cortés, C., Rebolledo-Maldonado, C., Ocampo-Botero, C., Rivera-Ordoñez, C., Saavedra-Trujillo, C., Figueroa-Restrepo, C., Agudelo-López, C., Jaramillo-Villegas, C., Villaquirán-Torres, C., Rodríguez-Ariza, D., Rincón-Valenzuela, D., Lemus-Rojas, M., Pinto-Pinzón, D., Garzón-Díaz, D., Cubillos-Apolinar, D., Beltrán-Linares, E., Kondo-Rodríguez, E., Yama-Mosquera, E., Polania-Fierro, E., Real-Urbina, E., Rosas-Romero, A., Mendoza-Beltrán, F., Guevara-Pulido, F., Celia-Márquez, G., Ramos-Ramos, G., Prada-Martínez, G., León-Basantes, G., Liévano-Sánchez, G., Ortíz-Ruíz, G., Barreto-García, G., Ibagón-Nieto, H., Idrobo-Quintero, H., Martínez-Ramírez, I., Solarte-Rodríguez, I., Quintero-Barrios, J., Arenas-Gamboa, J., Pérez-Cely, J., Castellanos-Parada, J., Garzón-Martínez, F., Luna-Ríos, J., Lara-Terán, J., Vargas-Rodríguez, J., Dueñas-Villamil, R., Bohórquez-Reyes, V., Martínez-Acosta, C., Gómez-Mesa, E., Gaitán-Rozo, J., Cortes-Colorado, J., Coral-Casas, J., Horlandy-Gómez, L., Bautista-Toloza, L., Palacios, L. P., Fajardo-Latorre, L., Pino-Villarreal, L., Rojas-Puentes, L., Rodríguez-Sánchez, P., Herrera-Méndez, M., Orozco-Levi, M., Sosa-Briceño, M., Moreno-Ruíz, N., Sáenz-Morales, O., Amaya-González, P., Ramírez-García, S., Nieto-Estrada, V., Carballo-Zárate, V., Abello-Polo, V.

Acevedo-Peña, J., Yomayusa-González, N., Cantor-Cruz, F., Pinzón-Flórez, C., Barrero-Garzón, L., De-La-Hoz-Siegler, I., Low-Padilla, E., Ramírez-Cerón, C., Combariza-Vallejo, F., Arias-Barrera, C., Moreno-Cortés, J., Rozo-Vanstrahlen, J., Correa-Pérez, L., Rojas-Gambasica, J., González-González, C., La-Rotta-Caballero, E., Ruíz-Talero, P., Contreras-Páez, R., Lineros-Montañez, A., Ordoñez-Cardales, J., Escobar-Olaya, M., Izaguirre-Ávila, R., Campos-Guerra, J., Accini-Mendoza, J., Pizarro-Gómez, C., Patiño-Pérez, A., Flores-Rodríguez, J., Valencia-Moreno, A., Londoño-Villegas, A., Saavedra-Rodríguez, A., Madera-Rojas, A., Caballero-Arteagam, A., Díaz-Campos, A., Correa-Rivera, F., Mantilla-Reinaud, A., Becerra-Torres, Á, Peña-Castellanos, Á, Reina-Soler, A., Escobar-Suarez, B., Patiño-Escobar, B., Rodríguez-Cortés, C., Rebolledo-Maldonado, C., Ocampo-Botero, C., Rivera-Ordoñez, C., Saavedra-Trujillo, C., Figueroa-Restrepo, C., Agudelo-López, C., Jaramillo-Villegas, C., Villaquirán-Torres, C., Rodríguez-Ariza, D., Rincón-Valenzuela, D., Lemus-Rojas, M., Pinto-Pinzón, D., Garzón-Díaz, D., Cubillos-Apolinar, D., Beltrán-Linares, E., Kondo-Rodríguez, E., Yama-Mosquera, E., Polania-Fierro, E., Real-Urbina, E., Rosas-Romero, A., Mendoza-Beltrán, F., Guevara-Pulido, F., Celia-Márquez, G., Ramos-Ramos, G., Prada-Martínez, G., León-Basantes, G., Liévano-Sánchez, G., Ortíz-Ruíz, G., Barreto-García, G., Ibagón-Nieto, H., Idrobo-Quintero, H., Martínez-Ramírez, I., Solarte-Rodríguez, I., Quintero-Barrios, J., Arenas-Gamboa, J., Pérez-Cely, J., Castellanos-Parada, J., Garzón-Martínez, F., Luna-Ríos, J., Lara-Terán, J., Vargas-Rodríguez, J., Dueñas-Villamil, R., Bohórquez-Reyes, V., Martínez-Acosta, C., Gómez-Mesa, E., Gaitán-Rozo, J., Cortes-Colorado, J., Coral-Casas, J., Horlandy-Gómez, L., Bautista-Toloza, L., Palacios, L. P., Fajardo-Latorre, L., Pino-Villarreal, L., Rojas-Puentes, L., Rodríguez-Sánchez, P., Herrera-Méndez, M., Orozco-Levi, M., Sosa-Briceño, M., Moreno-Ruíz, N., Sáenz-Morales, O., Amaya-González, P., Ramírez-García, S., Nieto-Estrada, V., Carballo-Zárate, V., Abello-Polo, V..

adult article blood clotting test clinical decision making clinical practice complication consensus controlled study coronavirus disease 2019 drug therapy female hospitalization human male observational study outpatient pandemic qualitative analysis retrospective study thromboembolism thrombosis prevention anticoagulant agent ; 2020(Revista Colombiana de Cardiologia)

Article in English, Spanish | EMBASE | ID: covidwho-917411

ABSTRACT

ABSTRACT

Introduction:

recent studies have reported the occurrence of thrombotic phenomena or coagulopathy in patients with COVID-19. There are divergent positions regarding the prevention, diagnosis, and treatment of these phenomena, and current clinical practice is based solely on deductions by extension from retrospective studies, case series, observational studies, and international guidelines developed prior to the pandemic.

Objective:

to generate a group of recommendations on the prevention, diagnosis and management of thrombotic complications associated with COVID-19.

Methods:

a rapid guidance was carried out applying the GRADE Evidence to Decision (EtD) frameworks and an iterative participation system, with statistical and qualitative analysis.

Results:

31 clinical recommendations were generated focused on a) Coagulation tests in symptomatic adults with suspected infection or confirmed SARS CoV-2 infection;b) Thromboprophylaxis in adults diagnosed with COVID-19 (Risk scales, thromboprophylaxis for outpatient, in-hospital management, and duration of thromboprophylaxis after discharge from hospitalization), c) Diagnosis and treatment of thrombotic complications, and d) Management of people with previous indication of anticoagulant agents.

Conclusions:

recommendations of this consensus guide clinical decision-making regarding the prevention, diagnosis, and treatment of thrombotic phenomena in patients with COVID-19, and represent an agreement that will help decrease the dispersion in clinical practices according to the challenge imposed by the pandemic.

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Collection: Databases of international organizations Database: EMBASE Type of study: Observational study / Prognostic study / Qualitative research Country/Region as subject: South America / Colombia Language: English / Spanish Journal: Adult article blood clotting test clinical decision making clinical practice complication consensus controlled study coronavirus disease 2019 drug therapy female hospitalization human male observational study outpatient pandemic qualitative analysis retrospective study thromboembolism thrombosis prevention anticoagulant agent Document Type: Article

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