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Food-derived antioxidants and COVID-19.
Lammi, Carmen; Arnoldi, Anna.
  • Lammi C; Department of Pharmaceutical Science, University of Milan, Milan, Italy.
  • Arnoldi A; Department of Pharmaceutical Science, University of Milan, Milan, Italy.
J Food Biochem ; 45(1): e13557, 2021 01.
Article in English | MEDLINE | ID: covidwho-917749
ABSTRACT
SARS-CoV-2 (previously 2019-nCoV), the pathogenic agent of COVID-19 disease, started to expand from Wuhan, China, on December 2019 and in 2 months, it spread worldwide giving origin to a pandemic. COVID-19 has a stronger transmission capacity by inhalation of infectious aerosols and after an incubation time of 3-14 days, it may be responsible for diseases ranging from the asymptomatic to fatal consequences. COVID-19 has emerged as a multifaceted, multisystem, multi-organ disorder, which produces its pathogenic effects through a quite ubiquitous target at the level of multiple organs and in which oxidative stress and inflammatory process play relevant roles. Thus, besides the development of a pharmacological therapy, in the field of alternative and coadjutant therapeutic, the use of dietary supplements or nutraceuticals for the prevention or treatment of SARS-CoV-2 infection may be a useful strategy. Herein, we specifically comment on some literature evidences, which link the food-derived antioxidants and metal-chelating agents with treatment and prevention of oxidative stress and inflammation that play a key role in the progression of COVID-19. PRACTICAL APPLICATIONS Oxidative stress and inflammation are key factors increasing COVID-19 severity especially in the presence of chronic diseases associated with the antioxidant system fragility. These evidences support the recommendation of antioxidants supplementation as useful strategies against COVID-19. In light with these observations, herein, a comment which describes the major antioxidants and metal-chelating agents from food sources that might be useful for the treatment and prevention of oxidative stress and inflammation during COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Plant Extracts / COVID-19 / Antioxidants Type of study: Observational study / Prognostic study Topics: Traditional medicine Limits: Humans Language: English Journal: J Food Biochem Year: 2021 Document Type: Article Affiliation country: Jfbc.13557

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Plant Extracts / COVID-19 / Antioxidants Type of study: Observational study / Prognostic study Topics: Traditional medicine Limits: Humans Language: English Journal: J Food Biochem Year: 2021 Document Type: Article Affiliation country: Jfbc.13557