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Convalescent plasma for COVID-19: male gender, older age and hospitalisation associated with high neutralising antibody levels, England, 22 April to 12 May 2020.
Mehew, Jennifer; Johnson, Rachel; Roberts, David; Harvala, Heli.
  • Mehew J; Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, United Kingdom.
  • Johnson R; Statistics and Clinical Studies, NHS Blood and Transplant, Bristol, United Kingdom.
  • Roberts D; NHS Blood and Transplant, Oxford, United Kingdom.
  • Harvala H; Radcliffe Department of Medicine and BRC Haematology Theme, University of Oxford, John Radcliffe Hospital, Oxford, United Kingdom.
Euro Surveill ; 25(45)2020 11.
Article in English | MEDLINE | ID: covidwho-922779
ABSTRACT
We analysed factors associated with neutralising antibody levels in 330 convalescent plasma donors. Women and younger donors were more likely not to have measurable neutralising antibodies, while higher antibody levels were observed in men, in older donors and in those who had been hospitalised. These data will be of value in the timely recruitment of convalescent plasma donors most likely to have high levels of neutralising antibodies for ongoing studies investigating its effectiveness.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Blood Donors / Coronavirus Infections / Antibodies, Neutralizing / Betacoronavirus / Hospitalization / Antibodies, Viral Type of study: Diagnostic study Limits: Aged / Humans / Male Country/Region as subject: Europa Language: English Journal subject: Communicable Diseases Year: 2020 Document Type: Article Affiliation country: 1560-7917.Es.2020.25.45.2001754

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Blood Donors / Coronavirus Infections / Antibodies, Neutralizing / Betacoronavirus / Hospitalization / Antibodies, Viral Type of study: Diagnostic study Limits: Aged / Humans / Male Country/Region as subject: Europa Language: English Journal subject: Communicable Diseases Year: 2020 Document Type: Article Affiliation country: 1560-7917.Es.2020.25.45.2001754