Strategies for COVID-19 test in laboratory

ABSTRACT

Early and rapid laboratory test of Corona Virus Disease 2019(COVID-19) is crucial to the treatment of viral infection and monitoring of prognosis and is one of the most important means to improve the therapeutic effects. The traditional nucleic acid test based on polymerase chain reaction(PCR) and the protein test based on immune reaction are the main approaches for early and rapid tests. Each technique has its own advantages and disadvantages due to the limitations of the methodologies. Nonspecific laboratory indexes also have important value in the clinical diagnosis and treatment of patients with COVID-19. The approaches and strategies for COVID-19 test were explored in detail by focusing on nucleic acid, protein and routine laboratory indexes, and the joint detection of nucleic acid, protein and serological indexes is expected to be an important mean for clinical diagnosis of infectious diseases.