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Building a hemodiafiltration system from readily available components for continuous renal replacement therapy under disasters and pandemics: preparing for an acute kidney injury surge during COVID-19.
Hanna, Ramy M; Ferrey, Antoney; Rhee, Connie M; Sam, Ramin; Pearce, David; Kalantar-Zadeh, Kamyar; Don, Burl R.
  • Hanna RM; Division of Nephrology, Hypertension and Kidney Transplantation, Harold Simmons Center for Kidney Disease Research and Epidemiology.
  • Ferrey A; Division of Nephrology and Hypertension, University of California, Irvine, School of Medicine, Orange, CA, USA.
  • Rhee CM; Division of Nephrology, Hypertension and Kidney Transplantation, Harold Simmons Center for Kidney Disease Research and Epidemiology.
  • Sam R; Division of Nephrology and Hypertension, University of California, Irvine, School of Medicine, Orange, CA, USA.
  • Pearce D; Division of Nephrology, Hypertension and Kidney Transplantation, Harold Simmons Center for Kidney Disease Research and Epidemiology.
  • Kalantar-Zadeh K; Division of Nephrology and Hypertension, University of California, Irvine, School of Medicine, Orange, CA, USA.
  • Don BR; Department of Medicine, Division of Nephrology, University of California San Francisco, San Francisco, CA, USA.
Curr Opin Nephrol Hypertens ; 30(1): 93-96, 2021 01.
Article in English | MEDLINE | ID: covidwho-1024165
ABSTRACT
PURPOSE OF REVIEW The novel corona virus (SARS-CoV2) has been demonstrated to cause acute kidney injury due to direct cellular toxicity as well as due to a variety of autoimmune glomerular diseases. The concept of a surge of infected patients resulting in an overwhelming number of critical patients has been a central concern in healthcare planning during the COVID-19 era. RECENT

FINDINGS:

One crucial question remains as to how to manage patients with end stage renal disease and acute kidney injury in case of a massive surge of critically ill infected patients. Some publications address practical and ingenious solutions for just such a surge of need for renal replacement therapy. We present a plan for using a blood pump, readily available dialysis filter, and a prefilter and postfilter replacement fluid set up. This is in conjunction with multiple intravenous pumps to develop a simple hemofiltration apparatus.

SUMMARY:

The current set up may be a readily available option for use in critical situations where the need for renal replacement therapy outstrips the capacity of traditional hemodialysis services in a hospital or region.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Hemodiafiltration / Disasters / Acute Kidney Injury / Continuous Renal Replacement Therapy / SARS-CoV-2 / COVID-19 Type of study: Observational study Topics: Long Covid Limits: Humans Language: English Journal: Curr Opin Nephrol Hypertens Journal subject: Vascular Diseases / Nephrology Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Hemodiafiltration / Disasters / Acute Kidney Injury / Continuous Renal Replacement Therapy / SARS-CoV-2 / COVID-19 Type of study: Observational study Topics: Long Covid Limits: Humans Language: English Journal: Curr Opin Nephrol Hypertens Journal subject: Vascular Diseases / Nephrology Year: 2021 Document Type: Article