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Cardiac MRI in Children with Multisystem Inflammatory Syndrome Associated with COVID-19.
Blondiaux, Eléonore; Parisot, Pauline; Redheuil, Alban; Tzaroukian, Lucile; Levy, Yaël; Sileo, Chiara; Schnuriger, Aurélie; Lorrot, Mathie; Guedj, Romain; Ducou le Pointe, Hubert.
  • Blondiaux E; From the Department of Imaging (E.B., C.S., H.D.l.P.), Pediatric Cardiovascular Unit (P.P.), Neonatal and Pediatric Intensive Care Unit (L.T., Y.L.), Virology Laboratory (A.S.), Department of Pediatrics (M.L.), and Pediatric Emergency Department (R.G.), Hôpital Trousseau-Assistance Publique-Hôpitaux
  • Parisot P; From the Department of Imaging (E.B., C.S., H.D.l.P.), Pediatric Cardiovascular Unit (P.P.), Neonatal and Pediatric Intensive Care Unit (L.T., Y.L.), Virology Laboratory (A.S.), Department of Pediatrics (M.L.), and Pediatric Emergency Department (R.G.), Hôpital Trousseau-Assistance Publique-Hôpitaux
  • Redheuil A; From the Department of Imaging (E.B., C.S., H.D.l.P.), Pediatric Cardiovascular Unit (P.P.), Neonatal and Pediatric Intensive Care Unit (L.T., Y.L.), Virology Laboratory (A.S.), Department of Pediatrics (M.L.), and Pediatric Emergency Department (R.G.), Hôpital Trousseau-Assistance Publique-Hôpitaux
  • Tzaroukian L; From the Department of Imaging (E.B., C.S., H.D.l.P.), Pediatric Cardiovascular Unit (P.P.), Neonatal and Pediatric Intensive Care Unit (L.T., Y.L.), Virology Laboratory (A.S.), Department of Pediatrics (M.L.), and Pediatric Emergency Department (R.G.), Hôpital Trousseau-Assistance Publique-Hôpitaux
  • Levy Y; From the Department of Imaging (E.B., C.S., H.D.l.P.), Pediatric Cardiovascular Unit (P.P.), Neonatal and Pediatric Intensive Care Unit (L.T., Y.L.), Virology Laboratory (A.S.), Department of Pediatrics (M.L.), and Pediatric Emergency Department (R.G.), Hôpital Trousseau-Assistance Publique-Hôpitaux
  • Sileo C; From the Department of Imaging (E.B., C.S., H.D.l.P.), Pediatric Cardiovascular Unit (P.P.), Neonatal and Pediatric Intensive Care Unit (L.T., Y.L.), Virology Laboratory (A.S.), Department of Pediatrics (M.L.), and Pediatric Emergency Department (R.G.), Hôpital Trousseau-Assistance Publique-Hôpitaux
  • Schnuriger A; From the Department of Imaging (E.B., C.S., H.D.l.P.), Pediatric Cardiovascular Unit (P.P.), Neonatal and Pediatric Intensive Care Unit (L.T., Y.L.), Virology Laboratory (A.S.), Department of Pediatrics (M.L.), and Pediatric Emergency Department (R.G.), Hôpital Trousseau-Assistance Publique-Hôpitaux
  • Lorrot M; From the Department of Imaging (E.B., C.S., H.D.l.P.), Pediatric Cardiovascular Unit (P.P.), Neonatal and Pediatric Intensive Care Unit (L.T., Y.L.), Virology Laboratory (A.S.), Department of Pediatrics (M.L.), and Pediatric Emergency Department (R.G.), Hôpital Trousseau-Assistance Publique-Hôpitaux
  • Guedj R; From the Department of Imaging (E.B., C.S., H.D.l.P.), Pediatric Cardiovascular Unit (P.P.), Neonatal and Pediatric Intensive Care Unit (L.T., Y.L.), Virology Laboratory (A.S.), Department of Pediatrics (M.L.), and Pediatric Emergency Department (R.G.), Hôpital Trousseau-Assistance Publique-Hôpitaux
  • Ducou le Pointe H; From the Department of Imaging (E.B., C.S., H.D.l.P.), Pediatric Cardiovascular Unit (P.P.), Neonatal and Pediatric Intensive Care Unit (L.T., Y.L.), Virology Laboratory (A.S.), Department of Pediatrics (M.L.), and Pediatric Emergency Department (R.G.), Hôpital Trousseau-Assistance Publique-Hôpitaux
Radiology ; 297(3): E283-E288, 2020 12.
Article in English | MEDLINE | ID: covidwho-930393
ABSTRACT
This case series examines cardiac MRI findings in four children and adolescents admitted to intensive care in April 2020 for multisystem inflammatory syndrome and Kawasaki disease-like features related to coronavirus disease 2019 (COVID-19). Acute myocarditis occurred less than 1 week after onset of fever and gastrointestinal symptoms. Physical examination showed rash and cheilitis or conjunctivitis. All patients recovered after intravenous immunoglobulin therapy. Severe acute respiratory syndrome coronavirus 2 reverse transcription polymerase chain reaction was negative in nasopharyngeal, stool, and respiratory samples and was positive on serology. Cardiac MRI showed diffuse myocardial edema on T2 short tau inversion-recovery sequences and native T1 mapping, with no evidence of late gadolinium enhancement suggestive of replacement fibrosis or focal necrosis. These findings favor postinfectious myocarditis in children and adolescents with COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Magnetic Resonance Imaging / Coronavirus Infections / Systemic Inflammatory Response Syndrome Type of study: Prognostic study Topics: Long Covid Limits: Child / Female / Humans / Male Language: English Journal: Radiology Year: 2020 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Magnetic Resonance Imaging / Coronavirus Infections / Systemic Inflammatory Response Syndrome Type of study: Prognostic study Topics: Long Covid Limits: Child / Female / Humans / Male Language: English Journal: Radiology Year: 2020 Document Type: Article