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Coronapp: A web application to annotate and monitor SARS-CoV-2 mutations.
Mercatelli, Daniele; Triboli, Luca; Fornasari, Eleonora; Ray, Forest; Giorgi, Federico M.
  • Mercatelli D; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
  • Triboli L; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
  • Fornasari E; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
  • Ray F; Department of Systems Biology, Columbia University Medical Center, New York City, New York, USA.
  • Giorgi FM; Department of Pharmacy and Biotechnology, University of Bologna, Bologna, Italy.
J Med Virol ; 93(5): 3238-3245, 2021 05.
Article in English | MEDLINE | ID: covidwho-932449
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ABSTRACT
The avalanche of genomic data generated from the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus requires the development of tools to detect and monitor its mutations across the world. Here, we present a webtool, coronapp, dedicated to easily processing user-provided SARS-CoV-2 genomic sequences and visualizing the current worldwide status of SARS-CoV-2 mutations. The webtool allows users to highlight mutations and categorize them by frequency, country, genomic location and effect on protein sequences, and to monitor their presence in the population over time. The tool is available at http//giorgilab.unibo.it/coronannotator/ for the annotation of user-provided sequences. The full code is freely shared at https//github.com/federicogiorgi/giorgilab/tree/master/coronannotator.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Genome, Viral / SARS-CoV-2 / Mutation Limits: Humans Language: English Journal: J Med Virol Year: 2021 Document Type: Article Affiliation country: Jmv.26678

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Genome, Viral / SARS-CoV-2 / Mutation Limits: Humans Language: English Journal: J Med Virol Year: 2021 Document Type: Article Affiliation country: Jmv.26678