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Bimodular effects of D614G mutation on the spike glycoprotein of SARS-CoV-2 enhance protein processing, membrane fusion, and viral infectivity.
Jiang, Xiaoyi; Zhang, Zhengrong; Wang, Chenxi; Ren, Hongguang; Gao, Lihua; Peng, Haoran; Niu, Zubiao; Ren, He; Huang, Hongyan; Sun, Qiang.
  • Jiang X; Beijing Institute of Biotechnology, 20 Dongda Street, Beijing, 100071, China.
  • Zhang Z; Department of Oncology, Beijing Shijitan Hospital of Capital Medical University, 10 TIEYI Road, Beijing, 100038, China.
  • Wang C; Beijing Institute of Biotechnology, 20 Dongda Street, Beijing, 100071, China.
  • Ren H; Beijing Institute of Biotechnology, 20 Dongda Street, Beijing, 100071, China.
  • Gao L; Beijing Institute of Biotechnology, 20 Dongda Street, Beijing, 100071, China.
  • Peng H; Beijing Institute of Biotechnology, 20 Dongda Street, Beijing, 100071, China.
  • Niu Z; Department of Microbiology, Second Military Medical University, Shanghai, 200433, China.
  • Ren H; Beijing Institute of Biotechnology, 20 Dongda Street, Beijing, 100071, China.
  • Huang H; Beijing Institute of Biotechnology, 20 Dongda Street, Beijing, 100071, China.
  • Sun Q; Department of Oncology, Beijing Shijitan Hospital of Capital Medical University, 10 TIEYI Road, Beijing, 100038, China.
Signal Transduct Target Ther ; 5(1): 268, 2020 11 17.
Article in English | MEDLINE | ID: covidwho-933666
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2020 Document Type: Article Affiliation country: S41392-020-00392-4

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / Spike Glycoprotein, Coronavirus / SARS-CoV-2 / COVID-19 Type of study: Experimental Studies / Observational study Limits: Humans Language: English Journal: Signal Transduct Target Ther Year: 2020 Document Type: Article Affiliation country: S41392-020-00392-4