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Demographic & clinical profile of patients with COVID-19 at a tertiary care hospital in north India.
Soni, Shiv Lal; Kajal, Kamal; Yaddanapudi, L N; Malhotra, Pankaj; Puri, Goverdhan Dutt; Bhalla, Ashish; Singh, Mini P; Sehgal, Inderpaul Singh; Koushal, Vipin; Varma, Neelam; Biswal, Manisha; Lakshmi, P V M; Sharma, Sadhna; Suri, Vikas; Deepy, Z; Ram, Sant; Yadav, Jaivinder; Pandey, Navin; Sharma, Prashant; Malik, Nabhajit; Goyal, Kapil; Mehra, Aseem; Sahoo, Swapnajeet; Mohindra, Ritin; Francis, Jijo; Bhargava, Mudit; Singla, Karan; Babu, Preena; Verma, Amiy; Khaire, Niranjan Shiwaji; Guru, R R.
  • Soni SL; Department of Anaesthesia & Intensive Care, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Kajal K; Department of Anaesthesia & Intensive Care, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Yaddanapudi LN; Department of Anaesthesia & Intensive Care, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Malhotra P; Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Puri GD; Department of Anaesthesia & Intensive Care, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Bhalla A; Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Singh MP; Department of Virology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Sehgal IS; Department of Pulmonary Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Koushal V; Department of Hospital Administration, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Varma N; Department of Pathology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Biswal M; Department of Medical Microbiology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Lakshmi PVM; Department of Community Medicine & School of Public Health, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Sharma S; Department of Biochemistry, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Suri V; Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Deepy Z; Department of Biochemistry, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Ram S; Department of Biochemistry, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Yadav J; Department of Pediatrics, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Pandey N; Department of Hospital Administration, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Sharma P; Department of Hematology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Malik N; Department of Hematology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Goyal K; Department of Virology, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Mehra A; Department of Psychiatry, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Sahoo S; Department of Psychiatry, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Mohindra R; Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Francis J; Department of Anaesthesia & Intensive Care, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Bhargava M; Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Singla K; Department of Anaesthesia & Intensive Care, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Babu P; Department of Anaesthesia & Intensive Care, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Verma A; Department of Anaesthesia & Intensive Care, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Khaire NS; Department of Internal Medicine, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
  • Guru RR; Department of Hospital Administration, Postgraduate Institute of Medical Education & Research, Chandigarh, India.
Indian J Med Res ; 153(1 & 2): 115-125, 2021.
Article in English | MEDLINE | ID: covidwho-934551
ABSTRACT
BACKGROUND &

OBJECTIVES:

The COVID-19 pandemic emerged as a major public health emergency affecting the healthcare services all over the world. It is essential to analyze the epidemiological and clinical characteristics of patients with COVID-19 in different parts of our country. This study highlights clinical experience in managing patients with COVID-19 at a tertiary care centre in northern India.

METHODS:

Clinical characteristics and outcomes of consecutive adults patients admitted to a tertiary care hospital at Chandigarh, India, from April 1 to May 25, 2020 were studied. The diagnosis of SARS-CoV-2 infection was confirmed by real-time reverse transcriptase polymerase chain reaction (RT-PCR) on throat and/or nasopharyngeal swabs. All patients were managed according to the institute's consensus protocol and in accordance with Indian Council of Medical Research guidelines.

RESULTS:

During the study period, 114 patients with SARS-CoV-2 infection were admitted. The history of contact with COVID-19-affected individuals was available in 75 (65.8%) patients. The median age of the patients was 33.5 yr (13-79 yr), and there were 66 (58%) males. Of the total enrolled patients, 48 (42%) were symptomatic. The common presenting complaints were fever (37, 77%), cough (26, 54%) and shortness of breath (10, 20.8%). Nineteen (17%) patients had hypoxia (SpO2<94%) at presentation and 36 (31%) had tachypnoea (RR >24). Thirty four (29.8%) patients had an accompanying comorbid illness. Age more than 60 yr and presence of diabetes and hypertension were significantly associated with severe COVID-19 disease. Admission to the intensive care unit (ICU) was needed in 18 patients (52%), with three (2.6%) patients requiring assisted ventilation. Mortality of 2.6 per cent (3 patients) was observed. INTERPRETATION &

CONCLUSIONS:

Majority of the patients with COVID-19 infection presenting to our hospital were young and asymptomatic. Fever was noted only in three-fourth of the patients and respiratory symptoms in half of them. Patients with comorbidities were more vulnerable to complications. Triaged classification of patients and protocol-based treatment resulted in good outcomes and low case fatality.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / Tertiary Care Centers / COVID-19 Type of study: Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Asia Language: English Journal: Indian J Med Res Year: 2021 Document Type: Article Affiliation country: Ijmr.IJMR_2311_20

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / Tertiary Care Centers / COVID-19 Type of study: Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Asia Language: English Journal: Indian J Med Res Year: 2021 Document Type: Article Affiliation country: Ijmr.IJMR_2311_20