Loop-mediated isothermal amplification holds great potential for massive COVID-19 diagnostics

ABSTRACT

Real-time RT-PCR currently remains most popular for early COVID-19 diagnostics. However Loop-mediated isothermal amplification (LAMP) method outperform real-time RT-PCR in rapidity and simplicity because it doesn't require expensive laboratory equipment and trained personnel. LAMP-based diagnostic kits for COVID-19 testing are already exist, but LAMP-based tests are not yet widely adopted. The method has great potential for mass application. Here we discuss technical and methodological aspects of its widespread implementation.