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Recent advances in sensitive surface-enhanced Raman scattering-based lateral flow assay platforms for point-of-care diagnostics of infectious diseases.
Kim, Kihyun; Kashefi-Kheyrabadi, Leila; Joung, Younju; Kim, Kyeongnyeon; Dang, Hajun; Chavan, Sachin Ganpat; Lee, Min-Ho; Choo, Jaebum.
  • Kim K; Department of Chemistry, Chung-Ang University, Seoul, 06974, South Korea.
  • Kashefi-Kheyrabadi L; School of Integrative Engineering, Chung-Ang University, Seoul, 06974, South Korea.
  • Joung Y; Department of Chemistry, Chung-Ang University, Seoul, 06974, South Korea.
  • Kim K; Department of Chemistry, Chung-Ang University, Seoul, 06974, South Korea.
  • Dang H; Department of Chemistry, Chung-Ang University, Seoul, 06974, South Korea.
  • Chavan SG; School of Integrative Engineering, Chung-Ang University, Seoul, 06974, South Korea.
  • Lee MH; School of Integrative Engineering, Chung-Ang University, Seoul, 06974, South Korea.
  • Choo J; Department of Chemistry, Chung-Ang University, Seoul, 06974, South Korea.
Sens Actuators B Chem ; 329: 129214, 2021 Feb 15.
Article in English | MEDLINE | ID: covidwho-939272
ABSTRACT
This review reports the recent advances in surface-enhanced Raman scattering (SERS)-based lateral flow assay (LFA) platforms for the diagnosis of infectious diseases. As observed through the recent infection outbreaks of COVID-19 worldwide, a timely diagnosis of the disease is critical for preventing the spread of a disease and to ensure epidemic preparedness. In this regard, an innovative point-of-care diagnostic method is essential. Recently, SERS-based assay platforms have received increasing attention in medical communities owing to their high sensitivity and multiplex detection capability. In contrast, LFAs provide a user-friendly and easily accessible sensing platform. Thus, the combination of LFAs with a SERS detection system provides a new diagnostic modality for accurate and rapid diagnoses of infectious diseases. In this context, we briefly discuss the recent application of LFA platforms for the POC diagnosis of SARS-CoV-2. Thereafter, we focus on the recent advances in SERS-based LFA platforms for the early diagnosis of infectious diseases and their applicability for the rapid diagnosis of SARS-CoV-2. Finally, the key issues that need to be addressed to accelerate the clinical translation of SERS-based LFA platforms from the research laboratory to the bedside are discussed.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study / Prognostic study Language: English Journal: Sens Actuators B Chem Year: 2021 Document Type: Article Affiliation country: J.snb.2020.129214

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Diagnostic study / Prognostic study Language: English Journal: Sens Actuators B Chem Year: 2021 Document Type: Article Affiliation country: J.snb.2020.129214