Beyond the clot: perfusion imaging of the pulmonary vasculature after COVID-19.
Lancet Respir Med
; 9(1): 107-116, 2021 01.
Article
in English
| MEDLINE | ID: covidwho-939393
ABSTRACT
A compelling body of evidence points to pulmonary thrombosis and thromboembolism as a key feature of COVID-19. As the pandemic spread across the globe over the past few months, a timely call to arms was issued by a team of clinicians to consider the prospect of long-lasting pulmonary fibrotic damage and plan for structured follow-up. However, the component of post-thrombotic sequelae has been less widely considered. Although the long-term outcomes of COVID-19 are not known, should pulmonary vascular sequelae prove to be clinically significant, these have the potential to become a public health problem. In this Personal View, we propose a proactive follow-up strategy to evaluate residual clot burden, small vessel injury, and potential haemodynamic sequelae. A nuanced and physiological approach to follow-up imaging that looks beyond the clot, at the state of perfusion of lung tissue, is proposed as a key triage tool, with the potential to inform therapeutic strategies.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pulmonary Artery
/
Pulmonary Embolism
/
Pulmonary Fibrosis
/
Thrombosis
/
Computed Tomography Angiography
/
Ventilation-Perfusion Scan
/
COVID-19
Type of study:
Cohort study
/
Diagnostic study
/
Experimental Studies
/
Prognostic study
Topics:
Long Covid
Limits:
Humans
Language:
English
Journal:
Lancet Respir Med
Year:
2021
Document Type:
Article
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