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Post-lockdown SARS-CoV-2 nucleic acid screening in nearly ten million residents of Wuhan, China.
Cao, Shiyi; Gan, Yong; Wang, Chao; Bachmann, Max; Wei, Shanbo; Gong, Jie; Huang, Yuchai; Wang, Tiantian; Li, Liqing; Lu, Kai; Jiang, Heng; Gong, Yanhong; Xu, Hongbin; Shen, Xin; Tian, Qingfeng; Lv, Chuanzhu; Song, Fujian; Yin, Xiaoxv; Lu, Zuxun.
  • Cao S; Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Gan Y; Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Wang C; Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Bachmann M; Norwich Medical School, Faculty of Medicine and Health Science, University of East Anglia, Norwich, UK.
  • Wei S; Wuhan Municipal Health Commission, Wuhan, Hubei, China.
  • Gong J; Wuhan Centre for Clinical Laboratory, Wuhan, Hubei, China.
  • Huang Y; Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Wang T; Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Li L; Department of Management Science and Engineering, School of Economics and Management, Jiangxi Science and Technology Normal University, Nanchang, Jiangxi, China.
  • Lu K; Tongji Hospital, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Jiang H; Centre for Alcohol Policy Research, School of Psychology and Public Health, La Trobe University, Melbourne, VIC, Australia.
  • Gong Y; Melbourne School of Population and Global Health, University of Melbourne, Melbourne, VIC, Australia.
  • Xu H; Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Shen X; Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Tian Q; Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China.
  • Lv C; School of Public Health, Zhengzhou University, Zhengzhou, Henan, China.
  • Song F; Department of Emergency, Hainan Clinical Research Centre for Acute and Critical Diseases, The Second Affiliated Hospital of Hainan Medical University, Haikou, Hainan, China. lyuchuanzhu@hainmc.edu.cn.
  • Yin X; Norwich Medical School, Faculty of Medicine and Health Science, University of East Anglia, Norwich, UK. Fujian.song@uea.ac.uk.
  • Lu Z; Department of Social Medicine and Health Management, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei, China. yxx@hust.edu.cn.
Nat Commun ; 11(1): 5917, 2020 11 20.
Article in English | MEDLINE | ID: covidwho-939438
ABSTRACT
Stringent COVID-19 control measures were imposed in Wuhan between January 23 and April 8, 2020. Estimates of the prevalence of infection following the release of restrictions could inform post-lockdown pandemic management. Here, we describe a city-wide SARS-CoV-2 nucleic acid screening programme between May 14 and June 1, 2020 in Wuhan. All city residents aged six years or older were eligible and 9,899,828 (92.9%) participated. No new symptomatic cases and 300 asymptomatic cases (detection rate 0.303/10,000, 95% CI 0.270-0.339/10,000) were identified. There were no positive tests amongst 1,174 close contacts of asymptomatic cases. 107 of 34,424 previously recovered COVID-19 patients tested positive again (re-positive rate 0.31%, 95% CI 0.423-0.574%). The prevalence of SARS-CoV-2 infection in Wuhan was therefore very low five to eight weeks after the end of lockdown.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Nucleic Acids / Mass Screening / Coronavirus Infections / Betacoronavirus Type of study: Diagnostic study / Observational study Limits: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Asia Language: English Journal: Nat Commun Journal subject: Biology / Science Year: 2020 Document Type: Article Affiliation country: S41467-020-19802-w

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Nucleic Acids / Mass Screening / Coronavirus Infections / Betacoronavirus Type of study: Diagnostic study / Observational study Limits: Adolescent / Adult / Aged / Child / Female / Humans / Male / Middle aged / Young adult Country/Region as subject: Asia Language: English Journal: Nat Commun Journal subject: Biology / Science Year: 2020 Document Type: Article Affiliation country: S41467-020-19802-w