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A simple method to estimate flow restriction for dual ventilation of dissimilar patients: The BathRC model.
Plummer, Andrew R; du Bois, Jonathan L; Flynn, Joseph M; Roesner, Jens; Lee, Siu Man; Magee, Patrick; Thornton, Malcolm; Padkin, Andrew; Gill, Harinderjit S.
  • Plummer AR; Department of Mechanical Engineering, University of Bath, Bath, North Somerset, United Kingdom.
  • du Bois JL; Department of Mechanical Engineering, University of Bath, Bath, North Somerset, United Kingdom.
  • Flynn JM; Department of Mechanical Engineering, University of Bath, Bath, North Somerset, United Kingdom.
  • Roesner J; Department of Mechanical Engineering, University of Bath, Bath, North Somerset, United Kingdom.
  • Lee SM; Royal United Hospitals NHS Foundation Trust, Bath, North Somerset, United Kingdom.
  • Magee P; BMI Bath Clinic, Bath, North Somerset, United Kingdom.
  • Thornton M; Royal United Hospitals NHS Foundation Trust, Bath, North Somerset, United Kingdom.
  • Padkin A; Royal United Hospitals NHS Foundation Trust, Bath, North Somerset, United Kingdom.
  • Gill HS; Department of Mechanical Engineering, University of Bath, Bath, North Somerset, United Kingdom.
PLoS One ; 15(11): e0242123, 2020.
Article in English | MEDLINE | ID: covidwho-941704
ABSTRACT

BACKGROUND:

With large numbers of COVID-19 patients requiring mechanical ventilation and ventilators possibly being in short supply, in extremis two patients may have to share one ventilator. Careful matching of patient ventilation requirements is necessary. However, good matching is difficult to achieve as lung characteristics can have a wide range and may vary over time. Adding flow restriction to the flow path between ventilator and patient gives the opportunity to control the airway pressure and hence flow and volume individually for each patient. This study aimed to create and validate a simple model for calculating required flow restriction. METHODS AND

FINDINGS:

We created a simple linear resistance-compliance model, termed the BathRC model, of the ventilator tubing system and lung allowing direct calculation of the relationships between pressures, volumes, and required flow restriction. Experimental measurements were made for parameter determination and validation using a clinical ventilator connected to two test lungs. For validation, differing amounts of restriction were introduced into the ventilator circuit. The BathRC model was able to predict tidal lung volumes with a mean error of 4% (min1.2%, max9.3%).

CONCLUSION:

We present a simple model validated model that can be used to estimate required flow restriction for dual patient ventilation. The BathRC model is freely available; this tool is provided to demonstrate that flow restriction can be readily estimated. Models and data are available at DOI 10.15125/BATH-00816.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiration, Artificial / Ventilators, Mechanical / Coronavirus Infections Type of study: Prognostic study Limits: Humans Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2020 Document Type: Article Affiliation country: Journal.pone.0242123

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Respiration, Artificial / Ventilators, Mechanical / Coronavirus Infections Type of study: Prognostic study Limits: Humans Language: English Journal: PLoS One Journal subject: Science / Medicine Year: 2020 Document Type: Article Affiliation country: Journal.pone.0242123