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Antivirals With Adjunctive Corticosteroids Prevent Clinical Progression of Early Coronavirus 2019 Pneumonia: A Retrospective Cohort Study.
Ooi, Say Tat; Parthasarathy, Purnima; Lin, Yi; Nallakaruppan, Valliammai D/O; Ng, Shereen; Tan, Teck Choon; Low, Serena; Tang, Terence.
  • Ooi ST; Division of Infectious Diseases, Department of General Medicine, Khoo Teck Puat Hospital, Singapore.
  • Parthasarathy P; Clinical Epidemiology Unit, Khoo Teck Puat Hospital, Singapore.
  • Lin Y; Division of Infectious Diseases, Department of General Medicine, Khoo Teck Puat Hospital, Singapore.
  • Nallakaruppan VD; Clinical Epidemiology Unit, Khoo Teck Puat Hospital, Singapore.
  • Ng S; Division of General Medicine, Department of General Medicine, Khoo Teck Puat Hospital, Singapore.
  • Tan TC; Division of General Medicine, Department of General Medicine, Khoo Teck Puat Hospital, Singapore.
  • Low S; Division of Rheumatology, Department of General Medicine, Khoo Teck Puat Hospital, Singapore.
  • Tang T; Clinical Research Unit, Khoo Teck Puat Hospital, Singapore.
Open Forum Infect Dis ; 7(11): ofaa486, 2020 Nov.
Article in English | MEDLINE | ID: covidwho-944366
ABSTRACT
This is a retrospective cohort study of hospitalized adults with coronavirus disease 2019 (COVID-19). Fifty-seven patients received treatment alone, and 35 patients received treatment with adjunctive prednisolone. A combination of corticosteroids and antivirals was associated with lower risk of clinical progression and invasive mechanical ventilation or death in early COVID-19 pneumonia.
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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Observational study / Prognostic study Language: English Journal: Open Forum Infect Dis Year: 2020 Document Type: Article Affiliation country: Ofid

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Cohort study / Observational study / Prognostic study Language: English Journal: Open Forum Infect Dis Year: 2020 Document Type: Article Affiliation country: Ofid