Recent Approaches of Repositioning and Traditional Drugs for the Treatment of COVID-19 Pandemic Outbreak.
Mini Rev Med Chem
; 21(8): 952-968, 2021.
Article
in English
| MEDLINE | ID: covidwho-945506
ABSTRACT
The recent emergence of novel, pathogenic COVID-19 disease associated with SARSCoV- 2 virus in China and its rapid national and international spread pose a global health emergency. The development of a new drug is tedious and may take decades to develop and involve multiple steps like the development of prototypes and phase I to III human trials, which involve the study on small to large populations to examine the safety and side effects associated with the drug under trials. Due to continous increase in the number of confirmed cases and deaths, there is an urgent need to develop a drug that is effective to kill the SARS-CoV-2 virus with fewer side effects to the human body. Therefore, this review focus on the latest advances in the development for the treatment of COVID-19 disease associated with SARS-CoV-2 with repositioning of already marketed drug with small molecules, as well as Chinese traditional medicines with established safety and efficacy which are being used for different therapeutic uses.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Antiviral Agents
/
Disease Outbreaks
/
Drug Repositioning
/
Pandemics
/
SARS-CoV-2
/
COVID-19 Drug Treatment
Type of study:
Observational study
Limits:
Humans
Language:
English
Journal:
Mini Rev Med Chem
Journal subject:
Chemistry
Year:
2021
Document Type:
Article
Affiliation country:
1389557520666201124141103
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