Pancreatic Injury in COVID-19 Patients.
J Assoc Physicians India
; 68(12): 58-60, 2020 Dec.
Article
in English
| MEDLINE | ID: covidwho-946702
ABSTRACT
BACKGROUND AND AIM:
Coronavirus disease 2019 (COVID 2019) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) may cause multisystem dysfunction. We studied pancreatic injury (serum amylase and serum lipase levels) in COVID-19 patients.METHODS:
A retrospective study involving 42 COVID-19 patients (diagnosed by real-time PCR) admitted to a tertiary care hospital was conducted. Serum amylase and serum lipase levels were analysed in relation to severity of COVID-19 and mortality.RESULTS:
Mean age of patients was 50 ± 16 years, with male to female ratio of 3.71. Serum amylase was elevated in 14 patients (33%). Serum lipase was elevated in 7 out of 29 patients (24.1%). Mortality was seen in 18 patients (42.8%). Serum amylase or lipase did not correlate with severity of COVID-19 or its mortality. However, both patients who had high lipase (>3times) died.CONCLUSION:
The prevalence of hyperamylasemia in patients of COVID-19 was 33%, while that of elevated lipase was 24.1%. Pancreatic injury failed to show any statistically significant relation to severity or outcome of COVID-19.
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Collection:
International databases
Database:
MEDLINE
Main subject:
Pancreas
/
Pancreatic Diseases
/
Pneumonia, Viral
/
Coronavirus Infections
/
Pandemics
Type of study:
Observational study
/
Prognostic study
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
J Assoc Physicians India
Year:
2020
Document Type:
Article
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