Antigens, Differentiation, B-Lymphocyte/genetics; Betacoronavirus/physiology; Cathepsins/antagonists & inhibitors; DNA Transposable Elements/genetics; Ebolavirus/physiology; Genes, MHC Class II/genetics; Histocompatibility Antigens Class II/genetics; Antigen Presentation/genetics; Antigens, Differentiation, B-Lymphocyte/physiology; COVID-19; Cathepsins/physiology; Cell Line; Coronavirus Infections/prevention & control; Coronavirus Infections/virology; DNA Transposable Elements/physiology; Gene Knockout Techniques; Gene Silencing; Genes, MHC Class II/physiology; Hemorrhagic Fever, Ebola/prevention & control; Hemorrhagic Fever, Ebola/virology; Histocompatibility Antigens Class II/physiology; Humans; Pandemics/prevention & control; Pneumonia, Viral/prevention & control; Pneumonia, Viral/virology; Protein Isoforms/genetics; SARS-CoV-2; Transcriptional Activation/genetics; Virus Attachment; Virus Replication/physiology