Can COVID-19 pandemic boost the epidemic of neurodegenerative diseases?
Biol Direct
; 15(1): 28, 2020 11 27.
Article
in English
| MEDLINE | ID: covidwho-947943
ABSTRACT
The pandemic of Coronavirus Disease 2019 (COVID-19) presents the world with the medical challenge associated with multifactorial nature of this pathology. Indeed COVID-19 affects several organs and systems and presents diversified clinical picture. COVID-19 affects the brain in many ways including direct infection of neural cells with SARS-CoV-2, severe systemic inflammation which floods the brain with pro-inflammatory agents thus damaging nervous cells, global brain ischaemia linked to a respiratory failure, thromboembolic strokes related to increased intravascular clotting and severe psychological stress. Often the COVID-19 is manifested by neurological and neuropsychiatric symptoms that include dizziness, disturbed sleep, cognitive deficits, delirium, hallucinations and depression. All these indicate the damage to the nervous tissue which may substantially increase the incidence of neurodegenerative diseases and promote dementia.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Comorbidity
/
Neurodegenerative Diseases
/
Epidemics
/
Pandemics
/
COVID-19
Type of study:
Observational study
/
Prognostic study
Topics:
Long Covid
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Language:
English
Journal:
Biol Direct
Year:
2020
Document Type:
Article
Affiliation country:
S13062-020-00282-3
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