Therapeutic Drug Monitoring and Individualized Medication of Ribavirin
Chinese Pharmaceutical Journal
; 55(15):1229-1233, 2020.
Article
in Chinese
| Scopus | ID: covidwho-948225
ABSTRACT
Ribavirin is a widely used nucleoside antiviral drug. During the epidemic of coronavirus disease 2019 (COVID-19), ribavirin was recommended for empirical treatment in the Clinical Management of Human Infection with COVID-19 (trial guidance v6). However, due to the large inter-individual variations in dose-response relationship, and extremely long terminal half time, it is necessary to perform therapeutic drug monitoring and individualized dose adjustment for ribavirin in special populations. In this article, the pharmacokinetics and therapeutic drug monitoring of ribavirin in different populations are reviewed in order to provide reference for clinical rational use and individualized medication of ribavirin for treatment of COVID-19. Copyright 2020 by the Chinese Pharmaceutical Association.
Full text:
Available
Collection:
Databases of international organizations
Database:
Scopus
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
2020
Document Type:
Article
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