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GermiX: A skin friendly hand sanitizer with prolonged effectivity against pathogenic bacteria.
Balkrishna, Acharya; Singh, Kanchan; Singh, Hoshiyar; Haldar, Swati; Varshney, Anurag.
  • Balkrishna A; Drug Discovery and Development Division, Patanjali Research Institute (Governed By Patanjali Research Foundation Trust), Roorkee-Haridwar Road, Haridwar, Uttarakhand, 249405, India.
  • Singh K; Department of Allied and Applied Sciences, University of Patanjali, NH-58, Haridwar, Uttarakhand, 249405, India.
  • Singh H; Drug Discovery and Development Division, Patanjali Research Institute (Governed By Patanjali Research Foundation Trust), Roorkee-Haridwar Road, Haridwar, Uttarakhand, 249405, India.
  • Haldar S; Drug Discovery and Development Division, Patanjali Research Institute (Governed By Patanjali Research Foundation Trust), Roorkee-Haridwar Road, Haridwar, Uttarakhand, 249405, India.
  • Varshney A; Drug Discovery and Development Division, Patanjali Research Institute (Governed By Patanjali Research Foundation Trust), Roorkee-Haridwar Road, Haridwar, Uttarakhand, 249405, India.
AMB Express ; 10(1): 210, 2020 Dec 01.
Article in English | MEDLINE | ID: covidwho-951800
Semantic information from SemMedBD (by NLM)
1. Membrane PART_OF bacterial cell
Subject
Membrane
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bacterial cell
2. Hand Sanitizers compared_with Hand Sanitizers
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Hand Sanitizers
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compared_with
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Hand Sanitizers
3. Hand Sanitizers higher_than Hand Sanitizers
Subject
Hand Sanitizers
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higher_than
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Hand Sanitizers
4. Membrane PART_OF bacterial cell
Subject
Membrane
Predicate
PART_OF
Object
bacterial cell
5. Hand Sanitizers compared_with Hand Sanitizers
Subject
Hand Sanitizers
Predicate
compared_with
Object
Hand Sanitizers
6. Hand Sanitizers higher_than Hand Sanitizers
Subject
Hand Sanitizers
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higher_than
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Hand Sanitizers
ABSTRACT
COVID-19 pandemic has almost made hand sanitization a ritual resulting in a steep increase in the frequency of hand sanitization and an unprecedented surge in demand for hand sanitizers. In fact, several governments had to ration hand sanitizers in the retail outlets and over the counter chemist shops. Additionally, Indian government has put a cap on the prices of hand sanitizers. Currently, large sections of global and Indian population are grappling under financial crises. Therefore, mandatory hand sanitization has made an unwelcoming, yet unavoidable addition to the already-hard-to-maintain-grocery-list. Here, we have compared the anti-microbial efficacy of Patanjali Hand Sanitizer (PHS), developed and marketed by Patanjali Ayurved Ltd. (an India-based food and herbal medicine company) with one of the topmost hand sanitizers currently used under clinical set-ups. PHS has anti-microbial efficacy comparable to that of the standard hand sanitizer. Besides, disc diffusion and time-dependent thumb print assays showed that PHS has longer retentivity on the applied surfaces, suggesting lesser consumption of the sanitizer and concomitant relaxation on the monthly grocery budget. Observed anti-bacterial potency of PHS is attributed to the disruption of bacterial cell membrane, as employed by alcohol-based hand sanitizers. A rough estimation revealed that PHS is ~ 4.3 times cost effective than the standard hand sanitizer used as the positive control in this study. Taken together, PHS is a suitable alternative for existing hand sanitizers available in the market that can relax the demand-supply strain and soften significantly the burden of monthly expenditure on hand sanitizers.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: AMB Express Year: 2020 Document Type: Article Affiliation country: S13568-020-01151-y

Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: AMB Express Year: 2020 Document Type: Article Affiliation country: S13568-020-01151-y