Research progress in nervous system damage caused by SARS-CoV-2. / SARS-CoV-2对ç¥ç»ç³»ç»æ害çç 究è¿å±.
Zhong Nan Da Xue Xue Bao Yi Xue Ban
; 45(10): 1247-1254, 2020 Oct 28.
Article
in English, Chinese
| MEDLINE | ID: covidwho-955221
ABSTRACT
The coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a major outbreak in the world. SARS-CoV-2 infection can not only involve in the respiratory system, but also cause severe nervous system damage. Studies have shown that SRAS-CoV-2 can invade the nervous system through hematogenous and transneuronal pathways, and may cause nervous system damage in patients with COVID-19 by inhibiting cellular immunity, hypoxemia, inflammation, inducing neuronal degeneration and apoptosis, and angiotensin converting enzyme 2 (ACE2) mechanism. It can lead to intracranial infection, toxic encephalopathy, acute cerebrovascular disease, muscle damage, peripheral nervous system injury, acute myelitis, demyelination disease or other nervous system diseases.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Pneumonia, Viral
/
Coronavirus Infections
/
Betacoronavirus
/
COVID-19
Type of study:
Observational study
Limits:
Humans
Language:
English
/
Chinese
Journal:
Zhong Nan Da Xue Xue Bao Yi Xue Ban
Journal subject:
Medicine
Year:
2020
Document Type:
Article
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