Lesions in the lungs of fatal corona virus disease Covid-19.
Ann Anat
; 234: 151657, 2021 Mar.
Article
in English
| MEDLINE | ID: covidwho-956144
ABSTRACT
The corona virus outbreak in Wuhan, China, at the end of 2019 has rapidly evolved into a pandemic which is still virulent in many countries. An infection with SARS-CoV-2 can lead to corona virus disease (Covid-19). This paper presents an overview of the knowledge gained so far with regard to histopathological lung lesions in fatal courses of Covid-19. The main findings were diffuse alveolar damage and micro-angiopathies. These included the development of hyaline membranes, thrombi, endothelial inflammation, haemorrhages and angiogenesis. Overall, the vessel lesions seemed to be more lethal than the diffuse alveolar damage. There was obvious hyperreactivity and hyperinflammation of the cellular immune system. An expanded T-cell memory may explain the increased risk of a severe course in the elderly.
Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
SARS-CoV-2
/
COVID-19
/
Lung
Type of study:
Prognostic study
Limits:
Humans
Language:
English
Journal:
Ann Anat
Journal subject:
Anatomy
Year:
2021
Document Type:
Article
Affiliation country:
J.aanat.2020.151657
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