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Self-reported influenza and influenza-like symptoms in U.S. adults age 18-64 between September 1, 2019 and April 15, 2020.
Lennon, Robert P; Miller, Erin L; Snyder, Bethany; Van Scoy, Lauren Jodi.
  • Lennon RP; Penn State Milton S. Hershey Medical Center, Department of Family and Community Medicine, 500 University Drive, Hershey, PA, 17033, USA. Electronic address: rlennon@pennstatehealth.psu.edu.
  • Miller EL; Penn State Milton S. Hershey Medical Center, Department of Family and Community Medicine, 500 University Drive, Hershey, PA, 17033, USA. Electronic address: emiller22@pennstatehealth.psu.edu.
  • Snyder B; Penn State Milton S. Hershey Medical Center, Qualitative Mixed-Methods Core, 500 University Drive, Hershey, PA, 17033, USA. Electronic address: Bsnyder2@pennstatehealth.psu.edu.
  • Van Scoy LJ; Penn State Milton S. Hershey Medical Center, Department of Medicine, 500 University Drive, Hershey, PA, 17033, USA. Electronic address: lvanscoy@pennstatehealth.psu.edu.
J Clin Virol ; 134: 104709, 2021 01.
Article in English | MEDLINE | ID: covidwho-957191
ABSTRACT

BACKGROUND:

The Influenza-like Illness Surveillance Network (ILINet) can indicate the presence of novel, widespread community pathogens. Comparing week-to-week reported influenza-like illness percentages may identify the time of year a novel pathogen is introduced. However, changes in health-seeking behavior during the COVID-19 pandemic call in to question the reliability of 2019-2020 ILINet data as a comparison to prior years, potentially rendering this system less reliable as a novel pathogen surveillance tool. Corroboration of trends seen in the 2019-2020 ILINet data lends confidence to the validity of those trends. This study compares predicted versus reported influenza and influenza-like illnesses in vaccinated adults as a surrogate measure of novel pathogen surveillance.

METHODS:

An online survey was used to ask US adults their influenza vaccination status, whether they were diagnosed with influenza after vaccination, and whether they experienced an influenza-like illness other than flu.

RESULTS:

Prevalence of self-reported flu diagnosis in adults age 18-64 who received the flu vaccine between September 1, 2019 and April 15, 2020 (n = 3,225) was 5.8 %, while self-reported flu or flu-like illness (without a flu diagnosis) was 17.9 %.

CONCLUSION:

Flu and flu-like illness in this sample of flu-vaccinated U.S. adults is significantly higher than predicted, consistent with substantially higher ILI's in 2019-20 compared to ILI's from 2018-19, suggesting that the ILI values reported during the COVID-19 pandemic may be appropriate for comparison to prior years.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination / Influenza, Human / Pandemics / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Country/Region as subject: North America Language: English Journal: J Clin Virol Journal subject: Virology Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Vaccination / Influenza, Human / Pandemics / COVID-19 Type of study: Observational study / Prognostic study Topics: Vaccines Limits: Adolescent / Adult / Female / Humans / Male / Middle aged Country/Region as subject: North America Language: English Journal: J Clin Virol Journal subject: Virology Year: 2021 Document Type: Article