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Aortic thrombosis in COVID-19.
Wickham, Helena; Tam, Jerry C H; Chan, Xin Hui S; George, Marc J; Levi, Marcel; Brown, Michael.
  • Wickham H; Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London, UK.
  • Tam JCH; Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London, UK.
  • Chan XHS; Hospital for Tropical Diseases, University College London Hospitals NHS Foundation Trust, London, UK.
  • George MJ; Centre for Tropical Medicine and Global Health, Nuffield Department of Medicine, University of Oxford, Oxford, UK.
  • Levi M; Department of Clinical Pharmacology, University College London Hospitals NHS Foundation Trust, London, UK.
  • Brown M; Department of Medicine, University College London Hospitals NHS Foundation Trust, London, UK.
Clin Infect Pract ; 9: 100059, 2021 Jan.
Article in English | MEDLINE | ID: covidwho-959698
ABSTRACT

BACKGROUND:

Venous thrombo-embolism is now well-recognised as a common complication of severe COVID-19 disease. Arterial thrombosis has been less well recognised, although it is increasingly reported, mostly in the context of myocardial infarction and stroke. CASE REPORT A 63-year-old man developed a pale, cold foot with an absent dorsalis pedis pulse 7 days into his admission with COVID-19. A CT angiogram demonstrated a large thrombus in the lower thoracic aorta, which had not been present on CT pulmonary angiogram the preceding week, along with occlusion of both popliteal arteries. He was managed with therapeutic dose of low molecular weight heparin (LMWH) for 6 weeks.

RESULTS:

This case adds to the growing list of potential sites and consequences of thrombosis in COVID-19.

CONCLUSION:

This case underscores the urgent need for pathophysiological studies and clinical trials to target treatments and guidelines for thromboprophylaxis in COVID-19.

Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Prognostic study Language: English Journal: Clin Infect Pract Year: 2021 Document Type: Article Affiliation country: J.clinpr.2020.100059

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Full text: Available Collection: International databases Database: MEDLINE Type of study: Case report / Prognostic study Language: English Journal: Clin Infect Pract Year: 2021 Document Type: Article Affiliation country: J.clinpr.2020.100059