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Three-Dimensional Analysis of Particle Distribution on Filter Layers inside N95 Respirators by Deep Learning.
Lee, Hye Ryoung; Liao, Lei; Xiao, Wang; Vailionis, Arturas; Ricco, Antonio J; White, Robin; Nishi, Yoshio; Chiu, Wah; Chu, Steven; Cui, Yi.
  • Lee HR; Geballe Laboratory for Advanced Materials, Stanford University, Stanford, California 94305, United States.
  • Liao L; Stanford Institute for Materials and Energy Sciences, SLAC National Accelerator Laboratory, Menlo Park, California 94025, United States.
  • Xiao W; 4C Air, Inc., Sunnyvale, California 94089, United States.
  • Vailionis A; 4C Air, Inc., Sunnyvale, California 94089, United States.
  • Ricco AJ; Stanford Nano Shared Facility, Stanford University, Stanford, California 94305, United States.
  • White R; Department of Physics, Kaunas University of Technology, LT-51368 Kaunas, Lithuania.
  • Nishi Y; Department of Electrical Engineering, Stanford University, Stanford, California 94305, United States.
  • Chiu W; Carl Zeiss X-ray Microscopy, Inc., Pleasanton, California 94588, United States.
  • Chu S; Department of Electrical Engineering, Stanford University, Stanford, California 94305, United States.
  • Cui Y; Department of Bioengineering, James H. Clark Center, Stanford University, Stanford, California 94305, United States.
Nano Lett ; 21(1): 651-657, 2021 01 13.
Article in English | MEDLINE | ID: covidwho-962235
ABSTRACT
The global COVID-19 pandemic has changed many aspects of daily lives. Wearing personal protective equipment, especially respirators (face masks), has become common for both the public and medical professionals, proving to be effective in preventing spread of the virus. Nevertheless, a detailed understanding of respirator filtration-layer internal structures and their physical configurations is lacking. Here, we report three-dimensional (3D) internal analysis of N95 filtration layers via X-ray tomography. Using deep learning methods, we uncover how the distribution and diameters of fibers within these layers directly affect contaminant particle filtration. The average porosity of the filter layers is found to be 89.1%. Contaminants are more efficiently captured by denser fiber regions, with fibers <1.8 µm in diameter being particularly effective, presumably because of the stronger electric field gradient on smaller diameter fibers. This study provides critical information for further development of N95-type respirators that combine high efficiency with good breathability.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / N95 Respirators / SARS-CoV-2 / COVID-19 Limits: Humans Language: English Journal: Nano Lett Year: 2021 Document Type: Article Affiliation country: Acs.nanolett.0c04230

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pandemics / N95 Respirators / SARS-CoV-2 / COVID-19 Limits: Humans Language: English Journal: Nano Lett Year: 2021 Document Type: Article Affiliation country: Acs.nanolett.0c04230