Your browser doesn't support javascript.
The clinical and translational research activities at the INT - IRCCS "Fondazione Pascale" cancer center (Naples, Italy) during the COVID-19 pandemic.
Buonaguro, Franco M; Botti, Gerardo; Ascierto, Paolo Antonio; Pignata, Sandro; Ionna, Franco; Delrio, Paolo; Petrillo, Antonella; Cavalcanti, Ernesta; Di Bonito, Maurizio; Perdonà, Sisto; De Laurentiis, Michelino; Fiore, Francesco; Palaia, Raffaele; Izzo, Francesco; D'Auria, Stefania; Rossi, Virginia; Menegozzo, Simona; Piccirillo, Mauro; Celentano, Egidio; Cuomo, Arturo; Normanno, Nicola; Tornesello, Maria Lina; Saviano, Rocco; Barberio, Daniela; Buonaguro, Luigi; Giannoni, Giovanni; Muto, Paolo; Miscio, Leonardo; Bianchi, Attilio A M.
  • Buonaguro FM; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy. fm.buonaguro@istitutotumori.na.it.
  • Botti G; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Ascierto PA; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Pignata S; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Ionna F; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Delrio P; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Petrillo A; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Cavalcanti E; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Di Bonito M; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Perdonà S; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • De Laurentiis M; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Fiore F; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Palaia R; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Izzo F; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • D'Auria S; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Rossi V; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Menegozzo S; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Piccirillo M; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Celentano E; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Cuomo A; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Normanno N; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Tornesello ML; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Saviano R; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Barberio D; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Buonaguro L; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Giannoni G; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Muto P; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Miscio L; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy.
  • Bianchi AAM; Istituto Nazionale Tumori IRCCS Fondazione Pascale, Naples, Italy. a.bianchi@istitutotumori.na.it.
Infect Agent Cancer ; 15(1): 69, 2020 Nov 23.
Article in English | MEDLINE | ID: covidwho-965787
Semantic information from SemMedBD (by NLM)
1. Triage NEG_TREATS Patient in hospital
Subject
Triage
Predicate
NEG_TREATS
Object
Patient in hospital
2. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
3. Respiratory distress PROCESS_OF Workers
Subject
Respiratory distress
Predicate
PROCESS_OF
Object
Workers
4. Respiratory distress COEXISTS_WITH COVID-19
Subject
Respiratory distress
Predicate
COEXISTS_WITH
Object
COVID-19
5. Triage NEG_TREATS Patient in hospital
Subject
Triage
Predicate
NEG_TREATS
Object
Patient in hospital
6. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
7. Respiratory distress PROCESS_OF Workers
Subject
Respiratory distress
Predicate
PROCESS_OF
Object
Workers
8. Respiratory distress COEXISTS_WITH COVID-19
Subject
Respiratory distress
Predicate
COEXISTS_WITH
Object
COVID-19
ABSTRACT
COVID-19 pandemic following the outbreak in China and Western Europe, where it finally lost the momentum, is now devastating North and South America. It has not been identified the reason and the molecular mechanisms of the two different patterns of the pulmonary host responses to the virus from a minimal disease in young subjects to a severe distress syndrome (ARDS) in older subjects, particularly those with previous chronic diseases (including diabetes) and cancer. The Management of the Istituto Nazionale Tumori - IRCCS "Fondazione Pascale" in Naples (INT-Pascale), along with all Health professionals decided not to interrupt the treatment of those hospitalized and to continue, even if after a careful triage in order not to allow SARS-CoV-2 positive subjects to access, to take care of cancer patients with serious conditions. Although very few (n = 3) patients developed a symptomatic COVID-19 and required the transfer to a COVID-19 area of the Institute, no patients died during the hospitalization and completed their oncology treatment. Besides monitoring of the patients, all employees of the Institute (physicians, nurses, researchers, lawyers, accountants, gatekeepers, guardians, janitors) have been tested for a possible exposure. Personnel identified as positive, has been promptly subjected to home quarantine and subdued to health surveillance. One severe case of respiratory distress has been reported in a positive employees and one death of a family member. Further steps to home monitoring of COVID-19 clinical course have been taken with the development of remote Wi-Fi connected digital devices for the detection of early signs of respiratory distress, including heart rate and oxygen saturation.In conclusion cancer care has been performed and continued safely also during COVID-19 pandemic and further remote home strategies are in progress to ensure the appropriate monitoring of cancer patients.
Keywords

Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: Infect Agent Cancer Year: 2020 Document Type: Article Affiliation country: S13027-020-00330-7

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Language: English Journal: Infect Agent Cancer Year: 2020 Document Type: Article Affiliation country: S13027-020-00330-7