A prospective cohort study of the safety of breast cancer surgery during COVID-19 pandemic in the West of Scotland.
Breast
; 55: 1-6, 2021 Feb.
Article
in English
| MEDLINE | ID: covidwho-969026
ABSTRACT
INTRODUCTION:
In order to minimise the risk of breast cancer patients for COVID-19 infection related morbidity and mortality prioritisation of care has utmost importance since the onset of the pandemic. However, COVID-19 related risk in patients undergoing breast cancer surgery has not been studied yet. We evaluated the safety of breast cancer surgery during COVID-19 pandemic in the West of Scotland region.METHODS:
A prospective cohort study of patients having breast cancer surgery was carried out in a geographical region during the first eight weeks of the hospital lockdown and outcomes were compared to the regional cancer registry data of pre-COVID-19 patients of the same units (n = 1415).RESULTS:
188 operations were carried out in 179 patients. Tumour size was significantly larger in patients undergoing surgery during hospital lockdown than before (cT3-4 16.8% vs. 7.4%; p < 0.001; pT2 - pT4 45.5% vs. 35.6%; p = 0.002). ER negative and HER-2 positive rate was significantly higher during lockdown (ER negative 41.3% vs. 17%, p < 0.001; HER-2 positive 23.4% vs. 14.8%; p = 0.004). While breast conservation rate was lower during lockdown (58.6% vs. 65%; p < 0.001), level II oncoplastic conservation was significantly higher in order to reduce mastectomy rate (22.8% vs. 5.6%; p < 0.001). No immediate reconstruction was offered during lockdown. 51.2% had co-morbidity, and 7.8% developed postoperative complications in lockdown. There was no peri-operative COVID-19 infection related morbidity or mortality.CONCLUSION:
breast cancer can be safely provided during COVID-19 pandemic in selected patients.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Postoperative Complications
/
Breast Neoplasms
/
Cross Infection
/
COVID-19
/
Mastectomy
Type of study:
Cohort study
/
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Limits:
Adult
/
Aged
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
Europa
Language:
English
Journal:
Breast
Journal subject:
Endocrinology
/
Neoplasms
Year:
2021
Document Type:
Article
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