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A prospective cohort study of the safety of breast cancer surgery during COVID-19 pandemic in the West of Scotland.
Romics, Laszlo; Doughty, Julie; Stallard, Sheila; Mansell, James; Blackhall, Vivienne; Lannigan, Alison; Elgammal, Suzanne; Reid, Judith; McGuigan, Marie-Claire; Savioli, Francesca; Tovey, Sian; Murphy, Dermott; Reid, Iona; Malyon, Andy; McIlhenny, Jennifer; Wilson, Christopher.
  • Romics L; New Victoria Hospital, Greater Glasgow and Clyde Health Board, NHS Scotland, United Kingdom; Academic Unit of Surgery, College of Medical, Veterinary Sciences and Life, University of Glasgow, United Kingdom. Electronic address: Laszlo.Romics@glasgow.ac.uk.
  • Doughty J; Gartnavel General Hospital, Greater Glasgow and Clyde Health Board, NHS Scotland, United Kingdom.
  • Stallard S; Gartnavel General Hospital, Greater Glasgow and Clyde Health Board, NHS Scotland, United Kingdom.
  • Mansell J; University Hospital Wishaw, Lanarkshire Health Board, NHS Scotland, United Kingdom.
  • Blackhall V; New Victoria Hospital, Greater Glasgow and Clyde Health Board, NHS Scotland, United Kingdom.
  • Lannigan A; University Hospital Wishaw, Lanarkshire Health Board, NHS Scotland, United Kingdom.
  • Elgammal S; University Hospital Crosshouse, Ayrshire and Arran Health Board, NHS Scotland, United Kingdom.
  • Reid J; University Hospital Crosshouse, Ayrshire and Arran Health Board, NHS Scotland, United Kingdom.
  • McGuigan MC; New Victoria Hospital, Greater Glasgow and Clyde Health Board, NHS Scotland, United Kingdom.
  • Savioli F; Academic Unit of Surgery, College of Medical, Veterinary Sciences and Life, University of Glasgow, United Kingdom.
  • Tovey S; University Hospital Crosshouse, Ayrshire and Arran Health Board, NHS Scotland, United Kingdom.
  • Murphy D; University Hospital Wishaw, Lanarkshire Health Board, NHS Scotland, United Kingdom.
  • Reid I; New Victoria Hospital, Greater Glasgow and Clyde Health Board, NHS Scotland, United Kingdom.
  • Malyon A; Glasgow Royal Infirmary, Greater Glasgow and Clyde Health Board, NHS Scotland, United Kingdom.
  • McIlhenny J; University Hospital Wishaw, Lanarkshire Health Board, NHS Scotland, United Kingdom.
  • Wilson C; Gartnavel General Hospital, Greater Glasgow and Clyde Health Board, NHS Scotland, United Kingdom.
Breast ; 55: 1-6, 2021 Feb.
Article in English | MEDLINE | ID: covidwho-969026
ABSTRACT

INTRODUCTION:

In order to minimise the risk of breast cancer patients for COVID-19 infection related morbidity and mortality prioritisation of care has utmost importance since the onset of the pandemic. However, COVID-19 related risk in patients undergoing breast cancer surgery has not been studied yet. We evaluated the safety of breast cancer surgery during COVID-19 pandemic in the West of Scotland region.

METHODS:

A prospective cohort study of patients having breast cancer surgery was carried out in a geographical region during the first eight weeks of the hospital lockdown and outcomes were compared to the regional cancer registry data of pre-COVID-19 patients of the same units (n = 1415).

RESULTS:

188 operations were carried out in 179 patients. Tumour size was significantly larger in patients undergoing surgery during hospital lockdown than before (cT3-4 16.8% vs. 7.4%; p < 0.001; pT2 - pT4 45.5% vs. 35.6%; p = 0.002). ER negative and HER-2 positive rate was significantly higher during lockdown (ER negative 41.3% vs. 17%, p < 0.001; HER-2 positive 23.4% vs. 14.8%; p = 0.004). While breast conservation rate was lower during lockdown (58.6% vs. 65%; p < 0.001), level II oncoplastic conservation was significantly higher in order to reduce mastectomy rate (22.8% vs. 5.6%; p < 0.001). No immediate reconstruction was offered during lockdown. 51.2% had co-morbidity, and 7.8% developed postoperative complications in lockdown. There was no peri-operative COVID-19 infection related morbidity or mortality.

CONCLUSION:

breast cancer can be safely provided during COVID-19 pandemic in selected patients.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Postoperative Complications / Breast Neoplasms / Cross Infection / COVID-19 / Mastectomy Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Breast Journal subject: Endocrinology / Neoplasms Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Postoperative Complications / Breast Neoplasms / Cross Infection / COVID-19 / Mastectomy Type of study: Cohort study / Experimental Studies / Observational study / Prognostic study / Randomized controlled trials Limits: Adult / Aged / Female / Humans / Male / Middle aged Country/Region as subject: Europa Language: English Journal: Breast Journal subject: Endocrinology / Neoplasms Year: 2021 Document Type: Article