Your browser doesn't support javascript.
Clinical features of patients with coronavirus disease 2019 from a designated hospital in Beijing, China.
Sun, Lijun; Shen, Lijun; Fan, Junfen; Gu, Fengjun; Hu, Mei; An, Yiran; Zhou, Qing; Fan, Huahao; Bi, Jingfeng.
  • Sun L; Research Center for Clinical and Translational Medicine, Beijing 302 Hospital/The Fifth Medical Center of PLA General Hospital, Beijing, China.
  • Shen L; The First Liver Cirrhosis Diagnosis and Treatment Center, Beijing 302 Hospital/The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Fan J; Institute of Cerebrovascular Disease Research and Department of Neurology, Xuanwu Hospital of Capital Medical University, Beijing, China.
  • Gu F; Medical Information Center Department, Beijing 302 Hospital/The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Hu M; Library, Beijing 302 Hospital/The Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • An Y; The Medical Center of Clinical Laboratory, Beijing 302 Hospital/the Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Zhou Q; The Medical Center of Clinical Laboratory, Beijing 302 Hospital/the Fifth Medical Center of Chinese PLA General Hospital, Beijing, China.
  • Fan H; College of Life Science and Technology, Beijing University of Chemical Technology, Beijing, China.
  • Bi J; Research Center for Clinical and Translational Medicine, Beijing 302 Hospital/The Fifth Medical Center of PLA General Hospital, Beijing, China.
J Med Virol ; 92(10): 2055-2066, 2020 10.
Article in English | MEDLINE | ID: covidwho-969528
Semantic information from SemMedBD (by NLM)
1. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
2. Laboratory Infection PROCESS_OF Patients
Subject
Laboratory Infection
Predicate
PROCESS_OF
Object
Patients
3. Symptom severe PROCESS_OF Patients
Subject
Symptom severe
Predicate
PROCESS_OF
Object
Patients
4. exposure history PROCESS_OF Patients
Subject
exposure history
Predicate
PROCESS_OF
Object
Patients
5. Comorbidity PROCESS_OF Patients
Subject
Comorbidity
Predicate
PROCESS_OF
Object
Patients
6. Abnormal Finding PROCESS_OF Patients
Subject
Abnormal Finding
Predicate
PROCESS_OF
Object
Patients
7. Serum LOCATION_OF Ferritin
Subject
Serum
Predicate
LOCATION_OF
Object
Ferritin
8. Prognosis bad PROCESS_OF Patients
Subject
Prognosis bad
Predicate
PROCESS_OF
Object
Patients
9. COVID-19 PROCESS_OF Patients
Subject
COVID-19
Predicate
PROCESS_OF
Object
Patients
10. Laboratory Infection PROCESS_OF Patients
Subject
Laboratory Infection
Predicate
PROCESS_OF
Object
Patients
11. Symptom severe PROCESS_OF Patients
Subject
Symptom severe
Predicate
PROCESS_OF
Object
Patients
12. exposure history PROCESS_OF Patients
Subject
exposure history
Predicate
PROCESS_OF
Object
Patients
13. Comorbidity PROCESS_OF Patients
Subject
Comorbidity
Predicate
PROCESS_OF
Object
Patients
14. Abnormal Finding PROCESS_OF Patients
Subject
Abnormal Finding
Predicate
PROCESS_OF
Object
Patients
15. Serum LOCATION_OF Ferritin
Subject
Serum
Predicate
LOCATION_OF
Object
Ferritin
16. Prognosis bad PROCESS_OF Patients
Subject
Prognosis bad
Predicate
PROCESS_OF
Object
Patients
ABSTRACT
Clinical and laboratory data on patients with coronavirus disease 2019 (COVID-19) in Beijing, China, remain extremely limited. In this study, we summarized the clinical characteristics of patients with COVID-19 from a designated hospital in Beijing. In total, 55 patients with laboratory-confirmed SARS-CoV-2 infection in Beijing 302 Hospital were enrolled in this study. Demographic data, symptoms, comorbidities, laboratory values, treatments, and clinical outcomes were all collected and retrospectively analyzed. A total of 15 (27.3%) patients had severe symptoms, the mean age was 44.0 years (interquartile range [IQR], 34.0-56.0), and the median incubation period was 7.5 days (IQR, 5.0-11.8). A total of 26 (47.3%) patients had exposure history in Wuhan of less than 2 weeks, whereas 20 (36.4%) patients were associated with familial clusters. Also, eighteen (32.7%) patients had underlying comorbidities including hypertension. The most common symptom of illness was fever (45; 81.8%); 51 (92.7%) patients had abnormal findings on chest computed tomography. Laboratory findings showed that neutrophil count, percentage of lymphocyte, percentage of eosinophil, eosinophil count, erythrocyte sedimentation rate, albumin, and serum ferritin are potential risk factors for patients with a poor prognosis. A total of 26 patients (47.3%) were still hospitalized, whereas 29 (52.7%) patients had been discharged. Compared with patients in Wuhan, China, the symptoms of patients in Beijing are relatively mild. Older age, more comorbidities, and more abnormal prominent laboratory markers were associated with a severe condition. On the basis of antiviral drugs, it is observed that antibiotics treatment, appropriate dosage of corticosteroid, and gamma globulin therapy significantly improve patients' outcomes. Early identification and timely medical treatment are important to reduce the severity of patients with COVID-19.
Subject(s)
Keywords

Full text: Available Collection: International databases Database: MEDLINE Main subject: Coronary Disease / Diabetes Mellitus / COVID-19 / Hypertension / Kidney Failure, Chronic Type of study: Etiology study / Observational study / Prognostic study / Risk factors Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2020 Document Type: Article Affiliation country: Jmv.25966

Similar

MEDLINE

...
LILACS

LIS


Full text: Available Collection: International databases Database: MEDLINE Main subject: Coronary Disease / Diabetes Mellitus / COVID-19 / Hypertension / Kidney Failure, Chronic Type of study: Etiology study / Observational study / Prognostic study / Risk factors Country/Region as subject: Asia Language: English Journal: J Med Virol Year: 2020 Document Type: Article Affiliation country: Jmv.25966