COVID-19 in a liver transplant recipient: Could iatrogenic immunosuppression have prevented severe pneumonia? A case report.
World J Gastroenterol
; 26(44): 7076-7084, 2020 Nov 28.
Article
in English
| MEDLINE | ID: covidwho-972402
ABSTRACT
BACKGROUND:
Coronavirus disease (COVID) is a new and highly contagious infectious disease caused by the coronavirus (COVID-19 or severe acute respiratory syndrome coronavirus 2). There is limited data regarding the incidence and management of COVID-19 in immunocompromised patients' post-transplantation. In the pre-COVID-19 era, these patients were already at an increased risk of developing opportunistic infections. These often manifested with atypical symptoms. CASESUMMARY:
We report another case of uneventful COVID-19 pneumonia in a 58-year old male who was 18 mo' post liver transplantation. He received tacrolimus monotherapy since July 2019. The clinical manifestations included only epigastric pain radiating to the right hypochondrium, nausea and vomiting. He had no fevers, cough, shortness of breath, anosmia or dysgeusia even if the chest computed tomography scan revealed an extension of the multiple patchy ground-glass density shadows to the upper lobe of the left lung too. He was hospitalised and received a course of oral chloroquine (200 mg × 3 per day) for a period of 10 d. Interestingly, the COVID 19 infection was uneventful though there were no modifications to his tacrolimus dosing. He was successfully discharged. We performed subsequent follow-up via telemedicine.CONCLUSION:
In light of the current pandemic, it is even more important to identify how the liver recipient's patients present and are managed, especially for immunosuppression treatment.Keywords
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Immunosuppression Therapy
/
Liver Transplantation
/
SARS-CoV-2
/
COVID-19
/
Graft Rejection
Type of study:
Case report
/
Cohort study
/
Diagnostic study
/
Experimental Studies
/
Observational study
/
Prognostic study
Limits:
Humans
/
Male
/
Middle aged
Language:
English
Journal:
World J Gastroenterol
Journal subject:
Gastroenterology
Year:
2020
Document Type:
Article
Affiliation country:
Wjg.v26.i44.7076
Similar
MEDLINE
...
LILACS
LIS