Captisol and GS-704277, but Not GS-441524, Are Credible Mediators of Remdesivir's Nephrotoxicity.

Yan, Victoria C; Muller, Florian L

Yan, Victoria C; Muller, Florian L.

Yan VC; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer, Houston, Texas, USA victoriacyanide@gmail.com.
Muller FL; Department of Cancer Systems Imaging, University of Texas MD Anderson Cancer, Houston, Texas, USA.

Antimicrob Agents Chemother ; 64(12)2020 11 17.

Article in English | MEDLINE | ID: covidwho-973187

Subject(s)

COVID-19; Adenosine/analogs & derivatives; Adenosine Monophosphate/analogs & derivatives; Alanine/analogs & derivatives; Furans; Humans; Lung; Pandemics; Pyrroles; Renal Dialysis; SARS-CoV-2; Transplant Recipients; Triazines; beta-Cyclodextrins

Keywords

GS-441524; drug metabolism; prodrug; remdesivir; renal clearance

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Full text: Available Collection: International databases Database: MEDLINE Main subject: COVID-19 Limits: Humans Language: English Year: 2020 Document Type: Article Affiliation country: AAC.01920-20

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