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Risk factors associated with morbidity and mortality outcomes of COVID-19 patients on the 28th day of the disease course: a retrospective cohort study in Bangladesh.
Islam, M Z; Riaz, B K; Islam, A N M S; Khanam, F; Akhter, J; Choudhury, R; Farhana, N; Jahan, N A; Uddin, M J; Efa, S S.
  • Islam MZ; Department of Community Medicine, National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka1212, Bangladesh.
  • Riaz BK; Department of Public Health and Hospital Administration, National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka1212, Bangladesh.
  • Islam ANMS; Department of Public Health and Hospital Administration, National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka1212, Bangladesh.
  • Khanam F; Department of Parasitology, National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka1212, Bangladesh.
  • Akhter J; Department of Microbiology and Mycology, National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka1212, Bangladesh.
  • Choudhury R; Department of Microbiology and Mycology, National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka1212, Bangladesh.
  • Farhana N; Department of Microbiology and Mycology, National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka1212, Bangladesh.
  • Jahan NA; Department of Nutrition and Biochemistry, National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka1212, Bangladesh.
  • Uddin MJ; Department of Microbiology and Mycology, National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka1212, Bangladesh.
  • Efa SS; Department of Community Medicine, National Institute of Preventive and Social Medicine (NIPSOM), Mohakhali, Dhaka1212, Bangladesh.
Epidemiol Infect ; 148: e263, 2020 10 29.
Article in English | MEDLINE | ID: covidwho-974840
ABSTRACT
Diverse risk factors intercede the outcomes of coronavirus disease 2019 (COVID-19). We conducted this retrospective cohort study with a cohort of 1016 COVID-19 patients diagnosed in May 2020 to identify the risk factors associated with morbidity and mortality outcomes. Data were collected by telephone-interview and reviewing records using a questionnaire and checklist. The study identified morbidity and mortality risk factors on the 28th day of the disease course. The majority of the patients were male (64.1%) and belonged to the age group 25-39 years (39.4%). Urban patients were higher in proportion than rural (69.3% vs. 30.7%). Major comorbidities included 35.0% diabetes mellitus (DM), 28.4% hypertension (HTN), 16.6% chronic obstructive pulmonary disease (COPD), and 7.8% coronary heart disease (CHD). The morbidity rate (not-cured) was 6.0%, and the mortality rate (non-survivor) was 2.5%. Morbidity risk factors included elderly (AOR = 2.56, 95% CI = 1.31-4.99), having comorbidity (AOR = 1.43, 95% CI = 0.83-2.47), and smokeless tobacco use (AOR = 2.17, 95% CI = 0.84-5.61). The morbidity risk was higher with COPD (RR = 2.68), chronic kidney disease (CKD) (RR = 3.33) and chronic liver disease (CLD) (RR = 3.99). Mortality risk factors included elderly (AOR = 7.56, 95% CI = 3.19-17.92), having comorbidity (AOR = 5.27, 95% CI = 1.88-14.79) and SLT use (AOR = 1.93, 95% CI = 0.50-7.46). The mortality risk was higher with COPD (RR = 7.30), DM (RR = 2.63), CHD (RR = 4.65), HTN (RR = 3.38), CKD (RR = 9.03), CLD (RR = 10.52) and malignant diseases (RR = 9.73). We must espouse programme interventions considering the morbidity and mortality risk factors to condense the aggressive outcomes of COVID-19.
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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections Type of study: Cohort study / Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2020 Document Type: Article Affiliation country: S0950268820002630

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Pneumonia, Viral / Coronavirus Infections Type of study: Cohort study / Observational study / Prognostic study Limits: Adolescent / Adult / Aged / Child / Child, preschool / Female / Humans / Infant / Male / Middle aged Country/Region as subject: Asia Language: English Journal: Epidemiol Infect Journal subject: Communicable Diseases / Epidemiology Year: 2020 Document Type: Article Affiliation country: S0950268820002630