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Restarting LDLT During COVID-19: Early Results After Restructuring.
Jha, Sandeep K; Jamir, Imtiakum; Sisodia, Kshitij; Kumar, Niteen; Sood, Gaurav; Shanker, Nitin; Anand, Sachin; Dubey, Gaurav; Choudhary, Vinod; Lohia, Pankaj; Singhal, Amit; Wadhawan, Manav; Kumar, Ajay; Chaudhary, Abhideep.
  • Jha SK; Department of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India. Electronic address: drskjha@live.com.
  • Jamir I; Department of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India.
  • Sisodia K; Department of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India.
  • Kumar N; Department of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India.
  • Sood G; Department of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India.
  • Shanker N; Department of Liver Transplant Critical Care, BL Kapur Superspeciality Hospital, Delhi, India.
  • Anand S; Department of Liver Transplant Critical Care, BL Kapur Superspeciality Hospital, Delhi, India.
  • Dubey G; Department of Liver Transplant & HPB Anaesthesia, BL Kapur Superspeciality Hospital, Delhi, India.
  • Choudhary V; Department of Liver Transplant & HPB Anaesthesia, BL Kapur Superspeciality Hospital, Delhi, India.
  • Lohia P; Department of Liver Transplant Critical Care, BL Kapur Superspeciality Hospital, Delhi, India.
  • Singhal A; Department of Liver Transplant & HPB Anaesthesia, BL Kapur Superspeciality Hospital, Delhi, India.
  • Wadhawan M; Institute of Digestive and Liver Diseases, BL Kapur Superspeciality Hospital, Delhi, India.
  • Kumar A; Institute of Digestive and Liver Diseases, BL Kapur Superspeciality Hospital, Delhi, India.
  • Chaudhary A; Department of HPB Surgery & Liver Transplant, BL Kapur Superspeciality Hospital, Delhi, India.
Transplant Proc ; 53(4): 1118-1125, 2021 May.
Article in English | MEDLINE | ID: covidwho-978450
ABSTRACT

INTRODUCTION:

Living-donor liver transplantation (LDLT) has been mostly suspended and deceased-donor living transplantation activity has been considerably reduced because of coronavirus disease 2019 (COVID-19). We modified our protocols and procedures in line with COVID-19 guidelines. Since the restructuring, we have performed 20 LDLTs. Our study reports the outcomes of these cases and demonstrates the feasibility of LDLT during this pandemic. MATERIALS AND

METHODS:

The changes were influenced by experiences and communications from across the globe. A month-long self-imposed moratorium was spent in restructuring the program and implementing new protocols. Twenty LDLTs were performed between April 18 and September 15 using the new protocols. Our experience includes 2 simultaneous liver-kidney transplants, 1 ABO-incompatible LDLT, and 1 pediatric case (age 11 months).

RESULTS:

Nineteen patients recovered and 1 patient died. We maintained our postoperative immunosuppression protocol without many changes. Major complications were observed in 30% of recipients but none of the donors. One recipient was infected with COVID-19 during the postoperative period. A donor-recipient couple contracted COVID-19 after discharge from the hospital. All patients recovered from COVID-19 and liver enzymes were unaffected.

CONCLUSION:

This study represents a microcosm of experience in LDLT during the COVID-19 era. Outcomes of LDLT are not affected by COVID-19 per se, provided that we make necessary changes.
Subject(s)

Full text: Available Collection: International databases Database: MEDLINE Main subject: Postoperative Complications / Liver Transplantation / Infection Control / SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study / Qualitative research / Randomized controlled trials Limits: Adult / Female / Humans / Infant / Male / Middle aged Language: English Journal: Transplant Proc Year: 2021 Document Type: Article

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Postoperative Complications / Liver Transplantation / Infection Control / SARS-CoV-2 / COVID-19 Type of study: Observational study / Prognostic study / Qualitative research / Randomized controlled trials Limits: Adult / Female / Humans / Infant / Male / Middle aged Language: English Journal: Transplant Proc Year: 2021 Document Type: Article