Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa.

Heinrich, Fabian; Meißner, Kira; Langenwalder, Felicia; Püschel, Klaus; Nörz, Dominik; Hoffmann, Armin; Lütgehetmann, Marc; Aepfelbacher, Martin; Bibiza-Freiwald, Eric; Pfefferle, Susanne; Heinemann, Axel

Heinrich, Fabian; Meißner, Kira; Langenwalder, Felicia; Püschel, Klaus; Nörz, Dominik; Hoffmann, Armin; Lütgehetmann, Marc; Aepfelbacher, Martin; Bibiza-Freiwald, Eric; Pfefferle, Susanne; Heinemann, Axel.

Emerg Infect Dis ; 27(1)2021 01.

Article in English | MEDLINE | ID: covidwho-983633

ABSTRACT

ABSTRACT

Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding of nasopharyngeal viral RNA stability in 79 corpses showed no time-dependent decrease. Maintained infectivity is supported by virus isolation up to 35 hours postmortem.

Subject(s)

COVID-19/virology; Nasopharynx/virology; RNA, Viral/isolation & purification; Respiratory Mucosa/virology; SARS-CoV-2/isolation & purification; Cadaver; Humans

Keywords

2019 novel coronavirus disease; COVID-19; RNA stability; SARS-CoV-2; coronavirus; coronavirus disease; infectivity; postmortem; respiratory infections; severe acute respiratory syndrome coronavirus 2; viruses; zoonoses

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Full text: Available Collection: International databases Database: MEDLINE Main subject: RNA, Viral / Nasopharynx / Respiratory Mucosa / SARS-CoV-2 / COVID-19 Limits: Humans Language: English Journal subject: Communicable Diseases Year: 2021 Document Type: Article

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