Pre-Existing Cytokine and NLRP3 Inflammasome Activation and Increased Vascular Permeability in Diabetes: A Possible Fatal Link With Worst COVID-19 Infection Outcomes?

Lambadiari, Vaia; Kousathana, Foteini; Raptis, Athanasios; Katogiannis, Konstantinos; Kokkinos, Alexander; Ikonomidis, Ignatios

Lambadiari, Vaia; Kousathana, Foteini; Raptis, Athanasios; Katogiannis, Konstantinos; Kokkinos, Alexander; Ikonomidis, Ignatios.

Lambadiari V; 2ndDepartment of Internal Medicine, Research Unit and Diabetes Center, Medical School, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Kousathana F; 2ndDepartment of Internal Medicine, Research Unit and Diabetes Center, Medical School, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Raptis A; 2ndDepartment of Internal Medicine, Research Unit and Diabetes Center, Medical School, Attikon University Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Katogiannis K; 2ndCardiology Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.
Kokkinos A; 1stDepartment of Propaedeutic Internal Medicine, Medical School, Diabetes Center, Laiko Hospital, National and Kapodistrian University of Athens, Athens, Greece.
Ikonomidis I; 2ndCardiology Department, Attikon University Hospital, Medical School, National and Kapodistrian University of Athens, Athens, Greece.

Front Immunol ; 11: 557235, 2020.

Article in English | MEDLINE | ID: covidwho-983707

Subject(s)

COVID-19; Capillary Permeability/immunology; Cytokines/immunology; Diabetes Complications; Pandemics; SARS-CoV-2/immunology; Adult; Aged; COVID-19/complications; COVID-19/immunology; COVID-19/mortality; Diabetes Complications/etiology; Diabetes Complications/immunology; Diabetes Complications/mortality; Female; Humans; Male; Middle Aged; Risk Factors

Keywords

cytokine; diabetes; glycocalyx; inflammasome; inflammation

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Full text: Available Collection: International databases Database: MEDLINE Main subject: Capillary Permeability / Cytokines / Diabetes Complications / Pandemics / SARS-CoV-2 / COVID-19 Type of study: Prognostic study Topics: Long Covid Limits: Adult / Aged / Female / Humans / Male / Middle aged Language: English Journal: Front Immunol Year: 2020 Document Type: Article Affiliation country: Fimmu.2020.557235

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