Smoking and comorbidities are associated with COVID-19 severity and mortality in 565 patients treated in Turkey: a retrospective observational study.
Rev Assoc Med Bras (1992)
; 66(12): 1679-1684, 2020 Dec.
Article
in English
| MEDLINE | ID: covidwho-983853
ABSTRACT
OBJECTIVE:
We aimed to explore the prevalence of smoking rates and comorbidities and evaluate the relationship between them and disease severity and mortality in inpatients with COVID-19.METHODS:
COVID-19 patients were divided into the following groups clinic group, intensive care unit (ICU) group, survivors, and non-survivors. Non-COVID-19 patients were included as a control group. The groups were compared.RESULTS:
There was no difference between patients with and without COVID-19 in terms of smoking, asthma, diabetes, dementia, coronary artery disease (CAD), hypertension, chronic renal failure and arrhythmia (p>0.05). Older age (Odds ratio (OR), 1.061; 95% confidence interval (CI) 1.041-1.082; p< 0.0001), chronic obstructive pulmonary disease (COPD) (OR, 2.775; 95% CI 1.128-6.829; p=0.026) and CAD (OR, 2.696; 95% CI 1.216-5.974; p=0.015) were significantly associated with ICU admission. Current smoking (OR, 5.101; 95% CI 2.382-10.927; p<0.0001) and former smoking (OR, 3.789; 95% CI 1.845-7.780; p<0.0001) were risk factors for ICU admission. Older age (OR; 1.082; 95% CI 1.056-1.109; p<0.0001), COPD (OR, 3.213; 95% CI 1.224-8.431; p=0.018), CAD (OR, 6.252; 95% CI 2.171-18.004; p=0.001) and congestive heart failure (CHF) (OR, 5.917; 95% CI 1.069-32.258; p=0.042), were significantly associated with mortality. Current smoking (OR, 13.014; 95% CI 5.058-33.480; p<0.0001) and former smoking (OR, 6.507; 95% CI 2.731-15.501; p<0.0001) were also risk factors for mortality.CONCLUSION:
Smoking, older age, COPD, and CAD were risk factors for ICU admission and mortality in patients with COVID-19. CHF was not a risk factor for ICU admission; however, it was a risk factor for mortality.
Full text:
Available
Collection:
International databases
Database:
MEDLINE
Main subject:
Smoking
/
COVID-19
Type of study:
Experimental Studies
/
Observational study
/
Prognostic study
/
Randomized controlled trials
Topics:
Long Covid
Limits:
Adult
/
Aged
/
Humans
/
Middle aged
Country/Region as subject:
Asia
Language:
English
Journal:
Rev Assoc Med Bras (1992)
Year:
2020
Document Type:
Article
Affiliation country:
1806-9282.66.12.1679
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